{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:59:01Z","timestamp":1790258341801,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Peri\u2010implantitis poses a significant challenge to implant longevity, leading to progressive bone loss and potential implant failure. While reconstructive surgery has been proven effective in regenerating peri\u2010implant tissues, the long\u2010term stability of the regenerated tissues and the impact of supportive peri\u2010implant care (SPIC) on bone levels remains underexplored. This case study presents a 10\u2010year follow\u2010up of a patient treated with reconstructive surgery for peri\u2010implantitis and enrolled in a structured maintenance program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 68\u2010year\u2010old male with a failing implant in the mandibular right first molar was treated using a reconstructive approach involving surface decontamination, particulate bone grafts, and an acellular dermal matrix as a barrier. Three re\u2010entry procedures were performed over a 10\u2010year period: at 9 months for the second stage of the two\u2010step GBR procedure and at 8 and 10 years for implant placement to replace fractured teeth. These interventions allowed for direct clinical and radiographic assessment of bone\u2010level changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At 9 months, bone regeneration was observed with minor residual dehiscences. After 8 years, bone remodeling and crestal bone gain on the lingual aspect were noted in the absence of further surgical interventions. At 10 years, radiographic evaluations confirmed minimal changes in marginal bone levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The presented two\u2010stage regenerative approach successfully restored peri\u2010implant health and function over time while minimizing the patient's financial burden. The three re\u2010entry procedures provided direct clinical evidence of bone regeneration and demonstrated the positive impact of effective maintenance therapy on marginal bone levels and their long\u2010term stability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>The described regenerative treatment for peri\u2010implantitis may ensure long\u2010term satisfactory outcomes.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Supportive peri\u2010implant care (SPIC) is effective in preventing disease recurrence and may improve crestal bone levels over time.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>This study presents the case of a 68\u2010year\u2010old patient with a failing dental implant due to peri\u2010implantitis. The implant was treated by thoroughly cleaning its surface, placing bone grafts, and using a protective membrane to regenerate bone around the fixture and obtain disease resolution. The patient returned for three follow\u2010up surgeries over 10 years, providing a unique opportunity to directly examine bone stability around the implant. Direct observations revealed that the bone graft healed well within the first 9 months, and the regenerated peri\u2010implant bone remained stable with minimal changes for a decade. Regular check\u2010ups and cleanings also helped prevent disease recurrence and further bone loss. By saving the existing implant, the patient avoided the extra expenses of removing and replacing it. Overall, these results suggest that a regenerative surgical approach, combined with structured maintenance care, can help obtain disease resolution and maintain stable long\u2010term outcomes. This can improve comfort and function while reducing costs for patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cap.10359","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T07:29:38Z","timestamp":1783495778000},"page":"477-484","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bone stability after regenerative peri\u2010implantitis treatment: A 10\u2010year follow\u2010up case study"],"prefix":"10.1002","volume":"16","author":[{"given":"Stefano","family":"Parma\u2010Benfenati","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences Section of Periodontology University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3610-9951","authenticated-orcid":false,"given":"Marisa","family":"Roncati","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine School of Dentistry University of Ferrara  Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3158-6477","authenticated-orcid":false,"given":"Lucrezia","family":"Parma\u2010Benfenati","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine School of Dentistry University of Ferrara  Ferrara Italy"},{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6177-3000","authenticated-orcid":false,"given":"Paolo","family":"Nava","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034518792567"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12334"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13823"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12460"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12523"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14116"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13162"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13822"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.7488"},{"issue":"10","key":"e_1_2_10_11_1","first-page":"1541","article-title":"The care guidelines: consensus\u2010based clinical case reporting guideline development","volume":"53","author":"Gagnier JJ","year":"2013","journal-title":"BMJ Case Rep"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12957"},{"issue":"6","key":"e_1_2_10_13_1","first-page":"496","article-title":"Vertical ridge augmentation using a membrane technique associated with osseointegrated implants","volume":"14","author":"Simion M","year":"1994","journal-title":"Int J Periodontics Restorative Dent"},{"issue":"5","key":"e_1_2_10_14_1","first-page":"434","article-title":"Vertical ridge augmentation: surgical protocol and retrospective evaluation of 48 consecutively inserted implants","volume":"18","author":"Tinti C","year":"1998","journal-title":"Int J Periodontics Restorative Dent"},{"issue":"5","key":"e_1_2_10_15_1","first-page":"424","article-title":"Histologic evaluation of guided vertical ridge augmentation around implants in humans","volume":"19","author":"Parma\u2010Benfenati S","year":"1999","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.2374"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12791"},{"key":"e_1_2_10_18_1","first-page":"475","volume-title":"The importance of dedicated maintenance therapy for long\u2010term success. 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