{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:59:00Z","timestamp":1790258340842,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371007"],"award-info":[{"award-number":["82371007"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This retrospective analysis aims to assess the efficacy of microscope\u2010aided implant decontamination combined with surgical intervention for peri\u2010implantitis and identify factors influencing its success.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients diagnosed with peri\u2010implantitis in at least one implant and treated with microscope\u2010assisted implant surface decontamination combined with surgery were evaluated. Clinical and radiographic parameters were assessed at baseline, 1\u2010year, and 3\u2010year intervals. Disease resolution, defined as \u22641 bleeding site, probing depth (PD) \u22645\u00a0mm, and no bone loss &gt;0.5\u00a0mm, was the primary outcome. Multilevel regression analysis identified predictors affecting disease resolution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty\u2010three patients with 50 implants were included. The 1\u2010year success rate was 92% (N = 46), declining to 80% (N = 40) at 3 years and 76% (N = 38) at final evaluation (37\u201398 months). At the final visit, 89.4% of implants had PD \u22645\u00a0mm, with no suppuration (SUP) in 95.7% of cases. Deepest PD at baseline negatively impacted outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Microscope\u2010assisted implant decontamination combined with surgical treatment is effective for peri\u2010implantitis management long\u2010term, serving as a potential reference for implant decontamination procedures. Further randomized controlled trials should investigate this approach's effectiveness compared to non\u2010microscope\u2010assisted decontamination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>This is the first clinical study to our knowledge to demonstrate the long\u2010term efficacy (up to 8 years) of a microscope\u2010assisted, multi\u2010step decontamination protocol combined with surgery for treating peri\u2010implantitis.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The presented protocol achieved high disease resolution rates of 76%\u201392%, with significant improvements in probing depth, bleeding, and bone level.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Microscopic visualization ensures thorough implant surface cleaning, addressing a critical limitation of conventional blind debridement techniques.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>This study establishes a potential new standard of care for achieving predictable and sustainable outcomes in the management of advanced peri\u2010implantitis.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>Dental implants occasionally develop severe infections (peri\u2010implantitis) that damage supporting bone and gums, often leading to implant failure. To improve treatment, we combined surgery with high\u2010magnification dental microscopes for precise cleaning of contaminated implant surfaces\u2014enabling clinicians to visually confirm thorough decontamination\u2014followed by bone grafting to regenerate lost tissue. Evaluating 33 patients (50 infected implants) over 3+ years (average 4.5 years), we found 92% of implants successfully controlled infection at 1 year (minimal bleeding, shallow pockets \u22645\u00a0mm, no pus, stable bone), declining to 80% at 3 years and 76% at final follow\u2010up. Bleeding, pus, and deep pockets decreased significantly, while bone levels improved. Implants with deeper initial infections had lower success rates. This microscope\u2010assisted approach provides effective, lasting management of peri\u2010implantitis by enhancing cleaning accuracy during surgery, offering a promising clinical strategy. Future studies should compare it directly with non\u2010microscopic methods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cap.70036","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T12:41:12Z","timestamp":1770727272000},"page":"581-592","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Microscope\u2010assisted implant surface decontamination combined with surgical treatment for peri\u2010implantitis: A retrospective case series study"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8407-6396","authenticated-orcid":false,"given":"Yang","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Stomatology Xuzhou Central Hospital Southeast University Xuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Periodontics Nanjing Stomatological Hospital Affiliated Hospital of Medical School Institute of Stomatology Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2908-2407","authenticated-orcid":false,"given":"Kexin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Periodontics Nanjing Stomatological Hospital Affiliated Hospital of Medical School Institute of Stomatology Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahong","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Periodontics Nanjing Stomatological Hospital Affiliated Hospital of Medical School Institute of Stomatology Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dentistry People's Hospital of Longhua  Shenzhen 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