{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T15:00:37Z","timestamp":1774278037824,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The aim of the study is to report clinical outcomes of autogenous tooth transplantation (ATT) of fully developed third molars following the extraction of periodontally hopeless teeth as a part of the treatment of a stage III, grade C, molar\u2010incisor pattern (MIP) periodontitis case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 24\u2010year\u2010old female with stage III, grade C, MIP periodontitis was treated at Operative Unity of Dentistry, Azienda Unit\u00e0 Sanitaria Locale, Ferrara. Despite steps I and II of periodontal therapy, deep pockets and severe mobility remained at maxillary and mandibular right first molars, which were scheduled for extraction due to a hopeless periodontal prognosis. At the time of extraction, the maxillary and mandibular right third molars (18 and 48) were transplanted in the severely compromised sockets of 16 and 46, respectively. The patient received supportive periodontal care with a 4\u2010month frequency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At 24 months, both transplanted teeth efficiently contributed to the masticatory function. The monitoring of periodontal parameters showed periodontal depth (PD) \u2264 4\u00a0mm, and the bone level amounted to more than 50% of the root length at both sites. A clinical attachment loss of 5\u00a0mm was recorded only at the buccal site of the donor tooth 48. No signs of root resorption or endodontic lesions were present. Overall, the number of pockets with PD \u2265 4 decreased from 32 to 4, and the full mouth bleeding score from 76% to 32%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ATT can be a viable option to replace periodontally hopeless teeth in patients with severe periodontitis, contributing to the overall improvement of periodontal conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Autogenous tooth transplantation may represent a viable alternative for the rehabilitation of sites severely compromised by periodontitis in molar\u2010incisor pattern patients.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The periodontal ligament of the donor tooth can induce bone formation and regenerate periodontal tissues.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain Language Summary<\/jats:title>\n                    <jats:p>This case report describes a 24\u2010year\u2010old woman affected by a severe and rapidly progressing form of periodontitis mainly involving the molars. Despite conventional periodontal therapy, two molars were considered hopeless and required extraction. As part of the rehabilitation plan, the patient's wisdom teeth were used as donor teeth and transplanted into the extraction sites through\u00a0autogenous tooth transplantation (ATT). After 2 years of follow\u2010up and regular supportive periodontal care, both transplanted teeth remained stable and functional, showing no signs of complications. Moreover, the patient's overall periodontal condition showed marked improvement. This case highlights that, in carefully selected patients, ATT can represent a viable alternative to conventional tooth replacement methods for managing advanced periodontitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cap.70060","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T14:11:06Z","timestamp":1774275066000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tooth autotransplantation following extraction of periodontally hopeless teeth in a periodontitis patient"],"prefix":"10.1002","author":[{"given":"Alessandro","family":"Rizzi","sequence":"first","affiliation":[{"name":"Research Centre for the Study of Periodontal and Peri\u2010Implant Diseases University of Ferrara Ferrara Italy"},{"name":"Operative Unit of Dentistry Azienda Unit\u00e0 Sanitaria Locale (AUSL)  Ferrara 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