{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T12:24:43Z","timestamp":1787228683083,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Tuberculosis is widely recognized for its pulmonary manifestations; however, the oral cavity may serve as an early and overlooked site of disease. Although the tongue is the most affected region, gingival involvement is not rare and may cause severe mucogingival destruction. The nonspecific nature of these lesions frequently leads to diagnostic delay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 25\u2010year\u2010old female presented with a persistent gingival ulcer in the maxillary anterior region associated with progressive recession and soft\u2010tissue loss. Histopathologic examination demonstrated necrotizing granulomatous inflammation with multinucleated giant cells. Although Ziehl\u2013Neelsen staining was negative, chest radiography, sputum testing, and GeneXpert polymerase chain reaction confirmed tuberculosis with pulmonary involvement. Following 9 months of systemic anti\u2010tubercular therapy, residual severe mucogingival defects were managed using a modified split\u2013full\u2013split coronally advanced flap combined with a subepithelial connective tissue graft and periosteal compartment stabilization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Healing was uneventful. At 2\u2010year follow\u2010up, complete root coverage was achieved in the incisors and premolars, with approximately 95% root coverage at the maxillary canine. Increased gingival thickness, stable soft\u2010tissue margins, and resolution of hypersensitivity were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case highlights the importance of considering tuberculosis in the differential diagnosis of persistent gingival lesions and demonstrates that advanced periodontal plastic surgery can successfully rehabilitate extensive mucogingival defects following medical stabilization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Severe mucogingival destruction can occur as a rare manifestation of oral tuberculosis and may persist despite resolution of infection.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Accurate diagnosis relies on combining histopathologic findings with systemic and molecular investigations.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Modified periodontal plastic surgery techniques can achieve predictable root coverage and long\u2010term soft\u2010tissue stability in complex defects.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>Tuberculosis (TB) usually affects the lungs, but in rare cases, it can also involve the oral cavity. This report describes a young patient whose first sign of TB was a painful gum lesion that caused severe gingival recession and loss of tissue around several teeth. After medical treatment for TB, the infection resolved, but the significant mucosal damage did not resolve. To restore the lost tissue, the patient underwent advanced periodontal plastic surgery using a connective tissue graft and a specialized flap technique. The procedure restored most of the lost gum and improved both comfort and appearance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cap.70087","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T11:34:22Z","timestamp":1787225662000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mucogingival loss secondary to oral tuberculosis and its management using periodontal plastic surgery: A case report"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7218-0758","authenticated-orcid":false,"given":"Gerado J.","family":"Chacon Ramirez","sequence":"first","affiliation":[{"name":"Private Practice  Medellin Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5427-8220","authenticated-orcid":false,"given":"Hend","family":"Abulatifa","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7173-2511","authenticated-orcid":false,"given":"Maria A.","family":"Zamora","sequence":"additional","affiliation":[{"name":"Private practice  Barquisimeto Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5088-0936","authenticated-orcid":false,"given":"Vanessa","family":"Castillo","sequence":"additional","affiliation":[{"name":"Private practice  Ciudad Bol\u00edvar Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5067-7317","authenticated-orcid":false,"given":"Muhammad H. A.","family":"Saleh","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0596-1527","authenticated-orcid":false,"given":"Mariana","family":"Villarroel\u2010Dorrego","sequence":"additional","affiliation":[{"name":"Universidad Central de Venezuela &amp; Universidad Santa Mar\u00eda  Caracas Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2015.12.001"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/ccd.ccd_416_19"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2018.04.024"},{"key":"e_1_2_10_5_1","volume-title":"Oral Diseases in the Tropics","author":"Prabhu SR","year":"1992"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_97_19"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12094"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972\u2010124x.142460"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/jisp.jisp_48_18"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp\u2010journals\u201010024\u20101287"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/2348\u20103334.126772"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/1735\u20103327.104886"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.7860\/jcdr\/2014\/10080.5281"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4091937"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.96809"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.14290"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100722.2010.00725.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.06.015"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijtb.2016.09.019"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4800991"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/jomfp.JOMFP_174_19"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601\u20100825.2000.tb00317.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00036\u201020"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12003"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050038"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.10.1729"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080146"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/cap.10134"}],"container-title":["Clinical Advances in Periodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.70087","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cap.70087","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.70087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T11:34:24Z","timestamp":1787225664000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/cap.70087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,20]]},"references-count":27,"alternative-id":["10.1002\/cap.70087"],"URL":"https:\/\/doi.org\/10.1002\/cap.70087","archive":["Portico"],"relation":{},"ISSN":["2573-8046","2163-0097"],"issn-type":[{"value":"2573-8046","type":"print"},{"value":"2163-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,20]]},"assertion":[{"value":"2026-03-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"cap.70087"}}