{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:50:58Z","timestamp":1791352258510,"version":"4.3.1"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Management of inflammation at previously surgically treated periodontal sites represents a clinical challenge. Although surgical retreatment may be indicated in selected cases, a conservative non\u2010surgical approach may restore periodontal stability while avoiding the additional morbidity associated with repeated surgery. This case report describes the long\u2010term management of a previously surgically treated mandibular molar furcation using site\u2010specific non\u2010surgical retreatment combined with adjunctive application of a collagen\u2010based hydrogel.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 45\u2010year\u2010old non\u2010smoking male with a history of stage III, grade B periodontitis presented with persistent inflammation at a previously surgically treated mandibular first molar. Clinical examination revealed a 4\u2010mm mid\u2010buccal probing depth associated with bleeding on probing and Grade II furcation involvement. Following comprehensive periodontal re\u2010evaluation, the site was managed by meticulous non\u2010surgical re\u2010instrumentation and adjunctive application of a collagen\u2010based hydrogel as a conservative alternative before considering surgical re\u2010intervention. The patient was subsequently enrolled in an individualized supportive periodontal care program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Bleeding on probing resolved within 25 days and remained absent throughout the 6\u2010year follow\u2010up. Probing depth progressively decreased from 4\u00a0to 2\u00a0mm, while the previously inflamed furcation site became clinically stable and maintainable without requiring additional periodontal surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Within the limitations of a single case report, this case illustrates that a carefully executed conservative retreatment strategy, combining meticulous non\u2010surgical periodontal therapy, individualized supportive periodontal care, and adjunctive collagen hydrogel application, may successfully restore and maintain periodontal stability at a previously surgically treated furcation site while avoiding surgical re\u2010intervention. Controlled prospective studies are required to clarify the clinical contribution of adjunctive collagen hydrogels in the management of persistent periodontal defects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Non\u2010surgical re\u2010instrumentation may be considered before surgical re\u2010intervention in selected previously treated periodontal sites, provided that the clinical response is carefully re\u2010evaluated.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Molar furcation anatomy may limit non\u2010surgical instrumentation; periodontal surgery remains indicated when adequate access and control of inflammation cannot be achieved through a conservative approach.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>In this case, periodontal stability was maintained for 6 years within an individualized supportive periodontal care program; the independent contribution of the adjunctive collagen hydrogel cannot be determined.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>Periodontal disease can leave areas around teeth that are difficult to keep healthy, particularly around the roots of molar teeth where the anatomy is complex. When inflammation persists after previous periodontal surgery, another surgical procedure may sometimes be necessary. This report describes a patient with inflammation around the root\u2010division area of a lower molar that had been surgically treated several years earlier. Before considering another operation, the area was carefully cleaned without surgery, and a collagen\u2010based gel was applied as an additional part of the treatment. The patient was closely monitored and received regular professional periodontal care. Bleeding resolved after treatment, the area became easier to maintain, and clinical stability was preserved over 6 years without additional surgery. This case illustrates that, in carefully selected situations, a conservative approach followed by appropriate monitoring may be considered before repeating periodontal surgery. However, this is the experience of a single patient, and it cannot determine whether the collagen gel contributed to the favorable outcome or whether similar results would occur in other patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cap.70118","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:17:26Z","timestamp":1791350246000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010term stability after non\u2010surgical furcation retreatment with adjunctive collagen hydrogel"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3610-9951","authenticated-orcid":false,"given":"Marisa","family":"Roncati","sequence":"first","affiliation":[{"name":"Department of Translational Medicine School of Dentistry University of Ferrara  Ferrara 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