{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T13:25:32Z","timestamp":1775913932284,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,2,22]],"date-time":"2008-02-22T00:00:00Z","timestamp":1203638400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The mosquito <jats:italic>Aedes aegypti<\/jats:italic> is an increasing problem of public health, being the vector responsible for dengue and Yellow Fever in tropical and subtropical regions. The aim of this work was to determine the potential larvicidal activity of a series of meroterpenoids, compounds <jats:bold>1<\/jats:bold>\u2013<jats:bold>7<\/jats:bold>, previously obtained fungal secondary metabolites from <jats:italic>Penicillium<\/jats:italic> sp., against the third\u2010instar larvae of <jats:italic>A. aegypti.<\/jats:italic> The lethal concentrations (<jats:italic>LC<\/jats:italic><jats:sub>50<\/jats:sub> and <jats:italic>LC<\/jats:italic><jats:sub>90<\/jats:sub>) of <jats:bold>1<\/jats:bold>\u2013<jats:bold>7<\/jats:bold> were evaluated 24\u2005h after exposure. Dehydroaustin (<jats:bold>4<\/jats:bold>) was the most active meroterpenoid in the series, with an <jats:italic>LC<\/jats:italic><jats:sub>50<\/jats:sub> value of 2.9\u2005ppm, making it an attractive natural insecticide.<\/jats:p>","DOI":"10.1002\/cbdv.200890032","type":"journal-article","created":{"date-parts":[[2008,2,22]],"date-time":"2008-02-22T12:46:45Z","timestamp":1203684405000},"page":"341-345","source":"Crossref","is-referenced-by-count":30,"title":["Larvicidal Effects of Fungal Meroterpenoids in the Control of <i>Aedes aegypti<\/i> L., the Main Vector of Dengue and Yellow Fever"],"prefix":"10.1002","volume":"5","author":[{"given":"Regina","family":"Geris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edson","family":"Rodrigues\u2010Fo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helo\u00edsa\u2005Helena","family":"Garcia\u2005da\u2005Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ionizete","family":"Garcia\u2005da\u2005Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,2,22]]},"reference":[{"key":"e_1_2_1_1_2","first-page":"161","volume":"50","author":"Pinheiro F. 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