{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:00:14Z","timestamp":1767981614918,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T00:00:00Z","timestamp":1284595200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Comparison of the effectiveness of antioxidant activity of three thiol compounds,<jats:sc>D<\/jats:sc>\u2010penicillamine, reduced<jats:sc>L<\/jats:sc>\u2010glutathione, and 1,4\u2010dithioerythritol, expressed as a radical\u2010scavenging capacity based on the two independent methods, namely a decolorization 2,2\u2032\u2010azinobis[3\u2010ethylbenzothiazoline\u20106\u2010sulfonic acid] assay and a rotational viscometry, is reported. Particular concern was focused on the testing of potential free\u2010radical scavenging effects of thiols against hyaluronan degradation, induced by hydroxyl radicals. A promising, solvent\u2010independent, antioxidative function of 1,4\u2010dithioerythritol, comparable to that of a standard compound,<jats:italic>Trolox<\/jats:italic><jats:sup>\u00ae<\/jats:sup>, was confirmed by the 2,2\u2032\u2010azinobis[3\u2010ethylbenzothiazoline\u20106\u2010sulfonic acid] assay. The new potential antioxidant 1,4\u2010dithioerythritol exhibited very good solubility in a variety of solvents (<jats:italic>e.g.<\/jats:italic>, H<jats:sub>2<\/jats:sub>O, EtOH, and DMSO) and could be widely accepted and used as an effective antioxidant standard instead of a routinely used<jats:italic>Trolox<\/jats:italic><jats:sup>\u00ae<\/jats:sup>on 2,2\u2032\u2010azinobis[3\u2010ethylbenzothiazoline\u20106\u2010sulfonic acid] assay.<\/jats:p>","DOI":"10.1002\/cbdv.201000019","type":"journal-article","created":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T11:32:54Z","timestamp":1284636774000},"page":"2191-2200","source":"Crossref","is-referenced-by-count":17,"title":["An Alternative Standard for<i>Trolox<\/i>\u2010Equivalent Antioxidant\u2010Capacity Estimation Based on Thiol Antioxidants. Comparative 2,2\u2032\u2010Azinobis[3\u2010ethylbenzothiazoline\u20106\u2010sulfonic Acid] Decolorization and Rotational Viscometry Study Regarding Hyaluronan Degradation"],"prefix":"10.1002","volume":"7","author":[{"given":"Eva","family":"Hrab\u00e1rov\u00e1","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katar\u00edna","family":"Valachov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Rapta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ladislav","family":"\u0160olt\u00e9s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,9,16]]},"reference":[{"key":"e_1_2_1_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9861(02)00411-3"},{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.59566\/IJBS.2008.4255","volume":"4","author":"Luc R.","year":"2008","journal-title":"Int. J. Biomed. Sci."},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.2478\/s11696-007-0058-8"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.polymdegradstab.2009.05.007"},{"key":"e_1_2_1_5_2","first-page":"215","volume":"54","author":"Wlodek L.","year":"2002","journal-title":"Pol. J. Pharmacol."},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.200800261"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2006.12.007"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2008.05.026"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(92)90482-X"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(98)00315-3"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.200800075"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/bm070309b"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.2307\/3575771"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)81724-6"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00892a002"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelechem.2008.07.016"},{"key":"e_1_2_1_17_2","unstructured":"http:\/\/www.calbiochem.com."},{"key":"e_1_2_1_18_2","unstructured":"http:\/\/www.caymanchem.com."},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2003.12.030"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2008.09.033"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja01250a038"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2008.09.068"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.200590094"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcbdv.201000019","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.201000019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,30]],"date-time":"2024-03-30T14:31:49Z","timestamp":1711809109000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.201000019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1002\/cbdv.201000019"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.201000019","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}