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Structure of compound <jats:bold>1<\/jats:bold> was elucidated with the aid of IR, UV, NMR, and MS data, and chemical transformation <jats:italic>via<\/jats:italic> new allyloxy xanthone derivative (<jats:bold>2<\/jats:bold>). Compounds <jats:bold>1<\/jats:bold>\u2013<jats:bold>6<\/jats:bold> exhibited various levels of antioxidant and anti\u2010<jats:italic>\u03b1<\/jats:italic>\u2010glucosidase activities. Absorption and fluorescence spectroscopic studies on <jats:bold>1<\/jats:bold>\u2013<jats:bold>6<\/jats:bold> indicated that these compounds could interact with calf thymus DNA (CT\u2010DNA) through intercalation and with bovine serum albumin (BSA) in a static quenching process. Compound <jats:bold>1<\/jats:bold> was found to be significantly cytotoxic against human cancer cell lines HeLa, HCT116, and AGS, and weakly active against normal NIH 3T3 cell line.<\/jats:p>","DOI":"10.1002\/cbdv.201400055","type":"journal-article","created":{"date-parts":[[2015,3,13]],"date-time":"2015-03-13T07:47:38Z","timestamp":1426232858000},"page":"358-370","source":"Crossref","is-referenced-by-count":24,"title":["A New DNA\u2010Intercalative Cytotoxic Allylic Xanthone from <i>Swertia corymbosa<\/i>"],"prefix":"10.1002","volume":"12","author":[{"given":"Chokkalingam","family":"Uvarani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karuppannan","family":"Arumugasamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumarasamy","family":"Chandraprakash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathan","family":"Sankaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athar","family":"Ata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Palathurai Subramaniam","family":"Mohan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,13]]},"reference":[{"key":"e_1_2_1_1_2","unstructured":"R.\u2005N. 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