{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T03:59:01Z","timestamp":1776484741797,"version":"3.51.2"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,2,10]],"date-time":"2015-02-10T00:00:00Z","timestamp":1423526400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A new polychlorinated triphenyl diether named microsphaerol (<jats:bold>1<\/jats:bold>), has been isolated from the endophtic fungus <jats:italic>Microsphaeropsis<\/jats:italic> sp. An intensive phytochemical investigation of the endophytic fungus <jats:italic>Seimatosporium<\/jats:italic> sp., led to the isolation of a new naphthalene derivative named seimatorone (<jats:bold>2<\/jats:bold>) and eight known compounds, <jats:italic>i.e.<\/jats:italic>, 1\u2010(2,6\u2010dihydroxyphenyl)\u20103\u2010hydroxybutan\u20101\u2010one (<jats:bold>3<\/jats:bold>), 1\u2010(2,6\u2010dihydroxyphenyl)butan\u20101\u2010one (<jats:bold>4<\/jats:bold>), 1\u2010(2\u2010hydroxy\u20106\u2010methoxyphenyl)butan\u20101\u2010one (<jats:bold>5<\/jats:bold>), 5\u2010hydroxy\u20102\u2010methyl\u20104<jats:italic>H<\/jats:italic>\u2010chromen\u20104\u2010one (<jats:bold>6<\/jats:bold>), 2,3\u2010dihydro\u20105\u2010hydroxy\u20102\u2010methyl\u20104<jats:italic>H<\/jats:italic>\u2010chromen\u20104\u2010one (<jats:bold>7<\/jats:bold>), 8\u2010methoxynaphthalen\u20101\u2010ol (<jats:bold>8<\/jats:bold>), nodulisporins A and B (<jats:bold>9<\/jats:bold> and <jats:bold>10<\/jats:bold>, resp.), and daldinol (<jats:bold>11<\/jats:bold>). The structures of <jats:bold>1<\/jats:bold> and <jats:bold>2<\/jats:bold> were elucidated by detailed spectroscopic analysis including <jats:sup>1<\/jats:sup>H\u2010 and <jats:sup>13<\/jats:sup>C\u2010NMR, COSY, HMQC, HMBC, and HR\u2010EI\u2010MS, while the structures of the known compounds were deduced from comparison of their spectral data with those in the literature. Preliminary studies revealed that microsphaerol (<jats:bold>1<\/jats:bold>) showed good antibacterial activities against <jats:italic>B. Megaterium and E. coli<\/jats:italic>, and good antilagal and antifungal activities against <jats:italic>C. fusca, M. violaceum<\/jats:italic>, respectively. On the other hand, seimatorone (<jats:bold>2<\/jats:bold>) exhibited moderate antibacterial, antialgal, and antifungal activities.<\/jats:p>","DOI":"10.1002\/cbdv.201400098","type":"journal-article","created":{"date-parts":[[2015,2,13]],"date-time":"2015-02-13T02:41:12Z","timestamp":1423795272000},"page":"289-294","source":"Crossref","is-referenced-by-count":28,"title":["Microsphaerol and Seimatorone: Two New Compounds Isolated from the Endophytic Fungi, <i>Microsphaeropsis<\/i> sp. and <i>Seimatosporium<\/i> sp."],"prefix":"10.1002","volume":"12","author":[{"given":"Hidayat","family":"Hussain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Root","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farah","family":"Jabeen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Al\u2010Harrasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manzoor","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fazal","family":"Mabood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahid","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afzal","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan R.","family":"Green","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Schulz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karsten","family":"Krohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,10]]},"reference":[{"key":"e_1_2_1_1_2","doi-asserted-by":"publisher","DOI":"10.3987\/COM-07-S(W)10"},{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200900749"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.200801052"},{"key":"e_1_2_1_4_2","first-page":"114","volume":"3","author":"Hussain H.","year":"2009","journal-title":"Rec. 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