{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:44:12Z","timestamp":1760784252730,"version":"3.41.2"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,5,29]],"date-time":"2017-05-29T00:00:00Z","timestamp":1496016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Institute for the Promotion of Teaching Science and Technology (IPST)"},{"name":"Research Fund for DPST Graduate with First Placement","award":["009\/2557"],"award-info":[{"award-number":["009\/2557"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>Phytochemical investigation from the tube roots of <jats:italic>Butea superba<\/jats:italic>, led to the isolation and identification of a new 2\u2010aryl\u20103\u2010benzofuranone named superbanone (<jats:bold>1<\/jats:bold>), one benzoin, 2\u2010hydroxy\u20101\u2010(2\u2010hydroxy\u20104\u2010methoxyphenyl)\u20102\u2010(4\u2010methoxyphenyl)ethanone (<jats:bold>2<\/jats:bold>), eight pterocarpans (<jats:bold>3<\/jats:bold>\u00a0\u2013\u00a0<jats:bold>10<\/jats:bold>), and eleven isoflavonoids (<jats:bold>11<\/jats:bold>\u00a0\u2013\u00a0<jats:bold>21<\/jats:bold>). Compound <jats:bold>2<\/jats:bold> was identified for the first time as a natural product. The structure of the isolated compounds was elucidated using spectroscopic methods, mainly 1D\u2010 and 2D\u2010<jats:styled-content style=\"fixed-case\">NMR<\/jats:styled-content>. The isolated compounds and their derivatives were evaluated for <jats:italic>\u03b1<\/jats:italic>\u2010glucosidase inhibitory and antimalarial activities. Compounds <jats:bold>3<\/jats:bold>,<jats:bold> 7<\/jats:bold>,<jats:bold> 8<\/jats:bold>, and <jats:bold>11<\/jats:bold> showed promising <jats:italic>\u03b1<\/jats:italic>\u2010glucosidase inhibitory activity (<jats:italic><jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content><\/jats:italic><jats:sub>50<\/jats:sub>\u00a0=\u00a013.71\u00a0\u00b1\u00a00.54, 23.54\u00a0\u00b1\u00a00.75, 28.83\u00a0\u00b1\u00a01.02, and 12.35\u00a0\u00b1\u00a00.36\u00a0\u03bc<jats:sc>m<\/jats:sc>, respectively). Compounds <jats:bold>3<\/jats:bold> and <jats:bold>11<\/jats:bold> were twofold less active than the standard drug acarbose (<jats:italic><jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content><\/jats:italic><jats:sub>50<\/jats:sub>\u00a0=\u00a06.54\u00a0\u00b1\u00a00.04\u00a0\u03bc<jats:sc>m<\/jats:sc>). None of the tested compounds was found to be active against <jats:italic>Plasmodium falciparum<\/jats:italic> strain 94. On the basis of biological activity results, structure\u2013activity relationships are discussed.<\/jats:p>","DOI":"10.1002\/cbdv.201700044","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T15:40:51Z","timestamp":1491406851000},"source":"Crossref","is-referenced-by-count":6,"title":["Superbanone, A New 2\u2010Aryl\u20103\u2010benzofuranone and Other Bioactive Constituents from the Tube Roots of <i>Butea superba<\/i>"],"prefix":"10.1002","volume":"14","author":[{"given":"Jutatip","family":"Boonsombat","sequence":"first","affiliation":[{"name":"Chulabhorn Research Institute Kamphaeng Phet 6 Road Bangkok 10210 Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vilailak","family":"Prachyawarakorn","sequence":"additional","affiliation":[{"name":"Chulabhorn Research Institute Kamphaeng Phet 6 Road Bangkok 10210 Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Acharavadee","family":"Pansanit","sequence":"additional","affiliation":[{"name":"School of Science Mae Fah Luang University Tasud, Muang Chiang Rai 57100 Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chulabhorn","family":"Mahidol","sequence":"additional","affiliation":[{"name":"Chulabhorn Research Institute Kamphaeng Phet 6 Road Bangkok 10210 Thailand"},{"name":"Chulabhorn Graduate Institute and Center for Environmental Health and Toxicology Kamphaeng Phet 6 Road Bangkok 10210 Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somsak","family":"Ruchirawat","sequence":"additional","affiliation":[{"name":"Chulabhorn Research Institute Kamphaeng Phet 6 Road Bangkok 10210 Thailand"},{"name":"Chulabhorn Graduate Institute and Center for Environmental Health and Toxicology Kamphaeng Phet 6 Road Bangkok 10210 Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanit","family":"Thongnest","sequence":"additional","affiliation":[{"name":"Chulabhorn Research Institute Kamphaeng Phet 6 Road Bangkok 10210 Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,29]]},"reference":[{"volume-title":"The remedy pamphlet of Kwao Krua tuber of Luang Anusarnsuntara\u2010kromkarnpiset","year":"1931","author":"Suntara A.","key":"e_1_2_8_2_1"},{"key":"e_1_2_8_3_1","first-page":"171","article-title":"Flavonoid and Flavonoid glycoside from Butea superba Roxb. and their cAMP phosphodiesterase inhibitory activity","volume":"25","author":"Roengsumran S.","year":"2000","journal-title":"J. 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