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The structures of the new compounds were assigned by mass spectrometric and 1D\u2010 and 2D\u2010<jats:styled-content style=\"fixed-case\">NMR<\/jats:styled-content> data. Known compounds were identified by comparison of <jats:sup>1<\/jats:sup>H\u2010<jats:styled-content style=\"fixed-case\">NMR<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> data with literature data. The two known neolignans <jats:bold>3<\/jats:bold> and <jats:bold>4<\/jats:bold> showed moderate antiplasmodial activity with the <jats:italic><jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content><\/jats:italic><jats:sub>50<\/jats:sub> values of 2.8 \u00b1 0.1 and 3.4 \u00b1 0.1 \u03bc<jats:sc>m<\/jats:sc>, respectively. Weak antiplasmodial activity was recorded for compounds <jats:bold>1<\/jats:bold>,<jats:bold> 2<\/jats:bold>,<jats:bold> 5<\/jats:bold>,<jats:bold> 6<\/jats:bold>,<jats:bold> 7<\/jats:bold>, and <jats:bold>8<\/jats:bold>, with the <jats:italic><jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content><\/jats:italic><jats:sub>50<\/jats:sub> values of 38 \u00b1 2, 23 \u00b1 2, 16.5 \u00b1 0.2, 86 \u00b1 1, 44 \u00b1 4, and 114 \u00b1 9 \u03bc<jats:sc>m<\/jats:sc>, respectively.<\/jats:p>","DOI":"10.1002\/cbdv.201700209","type":"journal-article","created":{"date-parts":[[2017,6,16]],"date-time":"2017-06-16T05:16:50Z","timestamp":1497590210000},"source":"Crossref","is-referenced-by-count":16,"title":["Bioactive Neolignans and Other Compounds from <i>Magnolia grandiflora<\/i> L.: Isolation and Antiplasmodial Activity"],"prefix":"10.1002","volume":"14","author":[{"given":"Abdul","family":"Latif","sequence":"first","affiliation":[{"name":"Department of Chemistry and Virginia Tech Center for Drug Discovery, M\/C 0212 Virginia Tech Blacksburg VA 24061 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongle","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Virginia Tech Center for Drug Discovery, M\/C 0212 Virginia Tech Blacksburg VA 24061 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema R.","family":"Dalal","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Virginia Tech Center for Drug Discovery, M\/C 0308 Virginia Tech Blacksburg VA 24061 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria L.","family":"Fern\u00e1ndez\u2010Murga","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Virginia Tech Center for Drug Discovery, M\/C 0308 Virginia Tech Blacksburg VA 24061 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio F.","family":"Merino","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Virginia Tech Center for Drug Discovery, M\/C 0308 Virginia Tech Blacksburg VA 24061 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria B.","family":"Cassera","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Virginia Tech Center for Drug Discovery, M\/C 0308 Virginia Tech Blacksburg VA 24061 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Goetz","sequence":"additional","affiliation":[{"name":"Natural Products Discovery Institute 3805 Old Easton Road Doylestown PA 18902 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G. 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