{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T13:01:43Z","timestamp":1778072503371,"version":"3.51.4"},"reference-count":38,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,9,20]],"date-time":"2017-09-20T00:00:00Z","timestamp":1505865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p>Evaluation of phytochemical constituents and antioxidant and antimicrobial activities of hexane (<jats:styled-content style=\"fixed-case\">PELH<\/jats:styled-content>), dichloromethane (<jats:styled-content style=\"fixed-case\">PELDCM<\/jats:styled-content>), ethyl acetate (<jats:styled-content style=\"fixed-case\">PELEA<\/jats:styled-content>), and Me<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">PELM<\/jats:styled-content>) extracts of young leaves of <jats:italic>Pseudocalymma elegans<\/jats:italic> have been carried out. Moreover, extracts have also been explored for the presence of sulphur containing compounds, 1,2\u2010dithiolane (<jats:bold>33<\/jats:bold>), diallyl disulfide (<jats:bold>35<\/jats:bold>), 3\u2010vinyl\u20101,2\u2010dithiacyclohex\u20105\u2010ene (<jats:bold>37<\/jats:bold>), and diallyl trisulfide (<jats:bold>38<\/jats:bold>) responsible for the garlic like smell of <jats:italic>P<\/jats:italic>. <jats:italic>elegans<\/jats:italic>. All the extracts were found to be antioxidant and showed potent inhibition with <jats:italic><jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content><\/jats:italic><jats:sub>50<\/jats:sub> values of 0.168 \u00b1 0.001, 0.128 \u00b1 0.002, 0.221 \u00b1 0.011, and 0.054 \u00b1 0.001, respectively, as compared to standard drugs ascorbic acid (<jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>) and butylated hydroxytoluene (<jats:styled-content style=\"fixed-case\">BHT<\/jats:styled-content>). The ethyl acetate extract (<jats:styled-content style=\"fixed-case\">PELE<\/jats:styled-content>) showed excellent activities against few <jats:italic>Gram<\/jats:italic>\u2010positive and <jats:italic>Gram<\/jats:italic>\u2010negative bacteria and some fungi as compared with standard drug ceftriaxone (3rd generation cephalosporin) and nystatin, respectively. Chemical constituents of hexane, dichloromethane, and ethyl acetate extracts were identified by gas chromatography\u2010mass spectrometry and mass spectral library search. Over all 55 chemical constituents were first time identified from the leaves which included branched and <jats:italic>n<\/jats:italic>\u2010hydrocarbons, fatty acids, fatty acid methyl esters, fatty alcohols, terpenes, alkaloid, vitamins, glycosides, aromatic compounds, and sulfur containing compounds. Two known chemical constituents, ursolic acid (<jats:bold>1<\/jats:bold>) and <jats:italic>\u03b2<\/jats:italic>\u2010amyrin (<jats:bold>2<\/jats:bold>), were also purified for the first time from the Me<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content> extract. To elucidate the structures of these compounds, <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IR<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> EI<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>, <jats:sup>1<\/jats:sup>H\u2010 and <jats:sup>13<\/jats:sup>C\u2010<jats:styled-content style=\"fixed-case\">NMR<\/jats:styled-content> spectroscopy were used.<\/jats:p>","DOI":"10.1002\/cbdv.201700222","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T17:34:40Z","timestamp":1499103280000},"source":"Crossref","is-referenced-by-count":3,"title":["Phytochemical and Biological Activities of <i>Pseudocalymma elegans<\/i>: A False Garlic"],"prefix":"10.1002","volume":"14","author":[{"given":"Sana","family":"Wahid","sequence":"first","affiliation":[{"name":"Department of Chemistry Federal Urdu University of Arts, Sciences and Technology Science Campus, Gulshan\u2010e\u2010Iqbal Karachi 75300 Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Ali","family":"Versiani","sequence":"additional","affiliation":[{"name":"Department of Chemistry Federal Urdu University of Arts, Sciences and Technology Science Campus, Gulshan\u2010e\u2010Iqbal Karachi 75300 Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sajid","family":"Jahangir","sequence":"additional","affiliation":[{"name":"Department of Chemistry Federal Urdu University of Arts, Sciences and Technology Science Campus, Gulshan\u2010e\u2010Iqbal Karachi 75300 Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khurshid","family":"Jawaid","sequence":"additional","affiliation":[{"name":"Department of Microbioloy Federal Urdu University of Arts, Science and Technology Ghulshan\u2010e\u2010Iqbal Karachi Sind 75300 Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Shafique","sequence":"additional","affiliation":[{"name":"Department of Microbioloy Federal Urdu University of Arts, Science and Technology Ghulshan\u2010e\u2010Iqbal Karachi Sind 75300 Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huma","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Chemistry Federal Urdu University of Arts, Sciences and Technology Science Campus, Gulshan\u2010e\u2010Iqbal Karachi 75300 Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaheen","family":"Faizi","sequence":"additional","affiliation":[{"name":"HEJ Research Institute of Chemistry International Center for Chemical and Biological Sciences University of Karachi Karachi 75270 Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/np200803m"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/np200906s"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-0101(00)00154-9"},{"key":"e_1_2_7_5_1","first-page":"249","volume-title":"The Davis and Hedge Festschrift: plant taxonomy, phytogeography and related subjects","author":"Dahlgren G.","year":"1989"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1095-8339.2003.t01-1-00158.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3417\/2003187"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(00)00313-7"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(00)82293-1"},{"key":"e_1_2_7_10_1","first-page":"195","article-title":"Intoxica\u00e7\u00e3o experimental por Pseudocalymma elegans (Vell.) 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