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Notably, Apiaceae essential oils may replace synthetic insecticides keeping most of their efficacy and avoiding environmental pollution and human poisoning. In the present work, we explored the insecticidal potential of the essential oils from five Apiaceae taxa, namely <jats:italic>Sison amomum<\/jats:italic>,<jats:italic> Echinophora spinosa<\/jats:italic>,<jats:italic> Heracleum sphondylium<\/jats:italic> subsp. <jats:italic>sphondylium<\/jats:italic>,<jats:italic> Heracleum sphondylium<\/jats:italic> subsp. <jats:italic>ternatum<\/jats:italic>, and <jats:italic>Trachyspemum ammi<\/jats:italic>, as well as their major constituents (sabinene, <jats:italic>p<\/jats:italic>\u2010cymene, terpinolene, myristicin, and thymol), against the filariasis vector <jats:italic>Culex quinquefasciatus<\/jats:italic>. For the purpose, the essential oils were obtained by hydrodistillation and their composition was achieved by gas chromatography\/mass spectrometry (<jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>). Their acute toxicity on third instar larvae of <jats:italic>C. quinquefasciatus<\/jats:italic> was determined. The two most active essential oils were those from <jats:italic>T. ammi<\/jats:italic> fruits and <jats:italic>E. spinosa<\/jats:italic> roots, showing <jats:italic>LC<\/jats:italic><jats:sub>50<\/jats:sub> below 20 \u03bcl\/l and <jats:italic>LD<\/jats:italic><jats:sub>90<\/jats:sub> below 50 \u03bcl\/l. These oils were dominated by the monoterpene phenol thymol and the phenylpropanoid myristicin, respectively, which showed the strongest larvicidal activity (<jats:italic>LC<\/jats:italic><jats:sub>50<\/jats:sub> of 15.1 and 16.3 \u03bcl\/l, respectively) among the pure compounds tested. These results showed that Apiaceae may be useful as source of larvicidal compounds to be used for the development of cheap, effective and eco\u2010friendly insecticidal formulations.<\/jats:p>","DOI":"10.1002\/cbdv.201700382","type":"journal-article","created":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T08:37:01Z","timestamp":1507538221000},"source":"Crossref","is-referenced-by-count":59,"title":["Larvicidal Activity of Essential Oils of Five Apiaceae Taxa and Some of Their Main Constituents Against <i>Culex quinquefasciatus<\/i>"],"prefix":"10.1002","volume":"15","author":[{"given":"Roman","family":"Pavela","sequence":"first","affiliation":[{"name":"Crop Research Institute Drnovska 507 161 06 Prague 6 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Maggi","sequence":"additional","affiliation":[{"name":"School of Pharmacy University of Camerino Via Sant'Agostino 1 62032 Camerino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Cianfaglione","sequence":"additional","affiliation":[{"name":"EA 2219 G\u00e9oarchitecture, UFR Sciences &amp; Techniques Universit\u00e9 de Bretagne Occidentale 6 Avenue Victor Le Gorgeu 29200 Brest France"},{"name":"School of Biosciences and Veterinary Medicine University of Camerino Via Pontoni, 5 62032 Camerino MC Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Bruno","sequence":"additional","affiliation":[{"name":"Department STEBICEF University of Palermo Viale delle Scienze, Parco d'Orleans II 90128 Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Benelli","sequence":"additional","affiliation":[{"name":"Department of Agriculture, Food and Environment University of Pisa via del Borghetto 80 56124 Pisa Italy"},{"name":"The BioRobotics Institute Scuola Superiore Sant'Anna Viale Rinaldo Piaggio 34 56025 Pontedera Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.200890000"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.201700096"},{"key":"e_1_2_7_4_1","volume-title":"Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics","author":"Leung A. 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