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Our results revealed that all hybrids <jats:bold>6a<\/jats:bold>\u00a0\u2013\u00a0<jats:bold>6o<\/jats:bold> had great potency against the tested strains, especially Gram\u2010negative pathogens. The synthesized hybrids were more potent than the parent 1\u2010[(1<jats:italic>R<\/jats:italic>,2<jats:italic>S<\/jats:italic>)\u20102\u2010fluorocyclopropyl]<jats:styled-content style=\"fixed-case\">CPFX<\/jats:styled-content> (<jats:bold>1<\/jats:bold>) and comparable to <jats:styled-content style=\"fixed-case\">CPFX<\/jats:styled-content> and levofloxacin against the majority of the tested pathogens, worth to be further investigated.<\/jats:p>","DOI":"10.1002\/cbdv.201800261","type":"journal-article","created":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T08:40:22Z","timestamp":1531212022000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Design, Synthesis and Antibacterial Evaluation of 1\u2010[(1<i>R<\/i>,2<i>S<\/i>)\u20102\u2010Fluorocyclopropyl]ciprofloxacin\u20101,2,4\u2010triazole\u20105(4<i>H<\/i>)\u2010thione Hybrids"],"prefix":"10.1002","volume":"15","author":[{"given":"Yang","family":"Gao","sequence":"first","affiliation":[{"name":"Xuanwu Hospital Capital Medical University Beijing 100053 P. 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