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The pentafluorophenyl derivative was efficacious against <jats:italic>T. brucei<\/jats:italic> with single digit micromolar EC<jats:sub>50<\/jats:sub> values and against <jats:italic>T. gondii<\/jats:italic> with even sub\u2010micromolar values. The 3\u2010chloro\u20104,5\u2010dimethoxyphenyl derivative showed an activity against amastigotes of <jats:italic>Leishmania major<\/jats:italic> parasites comparable to that of amphotericin B. In addition, antioxidant activities were observed for the bromophenyl derivatives, and their redox behavior was studied by cyclovoltammetry. Anti\u2010parasitic and antioxidative activities of the new naphthoquinone derivatives appear uncorrelated.<\/jats:p>","DOI":"10.1002\/cbdv.202000839","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T03:54:00Z","timestamp":1606276440000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["New Pyrano\u20104<i>H<\/i>\u2010benzo[<i>g<\/i>]chromene\u20105,10\u2010diones with Antiparasitic and Antioxidant Activities"],"prefix":"10.1002","volume":"18","author":[{"given":"Ibrahim S.","family":"Al Nasr","sequence":"first","affiliation":[{"name":"Department of Biology College of Science and Arts Qassim University  Unaizah 51911 Saudi Arabia"},{"name":"Department of Science Laboratories College of Science and Arts Qassim University  Ar Rass 51921 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Jentzsch","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Parasitology University of Bayreuth Universit\u00e4tsstrasse 30  95440 Bayreuth Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amin","family":"Shaikh","sequence":"additional","affiliation":[{"name":"Department of Chemistry Abeda Inamdar Senior College, 2390-B  K.B. 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