{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:12:08Z","timestamp":1790946728149,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T00:00:00Z","timestamp":1626134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31271842"],"award-info":[{"award-number":["31271842"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The characteristics of acidic polysaccharides extracted from <jats:italic>Daucus carota<\/jats:italic> L. var. sativa Hoffm were investigated and its hepatoprotective effects on alcoholic liver injury were determined in the mice model. A\u2005carrot polysaccharide (CPS\u2010I: Carrot polysaccharide\u2010I) with the molecular weight of 3.40\u00d710<jats:sup>4<\/jats:sup>\u2005kDa was isolated from <jats:italic>Daucus carota<\/jats:italic>\u2005L. and purified by diethylaminoethyl\u201052 and Sephadex G\u2010150 column chromatography. The components were analyzed by HPLC, which revealed that CPS\u2010I consisted of galacturonic acid, rhamnose, xylose, arabinose, fructose, and galactose at a relative ratio of 1\u2009:\u20093.16\u2009:\u20091.13\u2009:\u20095.53\u2009:\u20093.45\u2009:\u20097.76. Structural characterization analysis suggested that CPS\u2010I was mainly composed of \u21926)\u2010\u03b2\u2010D\u2010Galp\u2010(1\u2192 and \u21925)\u2010\u03b1\u2010L\u2010Araf\u2010(1\u2192. The hepatoprotective effect of CPS\u2010I was evaluated by alcoholic liver injury mice model.<\/jats:p><jats:p>The results showed that the administration of CPS\u2010I (300\u2005mg\/kg\/day) alleviated the alcoholic liver injury in mice by increasing the levels of ADH and ALDH and reducing oxidative stress. CPS\u2010I ameliorated the pathological changes of liver characterized by lipid accumulation, and reduced the number of lipid droplets.<\/jats:p>","DOI":"10.1002\/cbdv.202100359","type":"journal-article","created":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T14:16:53Z","timestamp":1624630613000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Characterization of an Acidic Polysaccharides from Carrot and Its Hepatoprotective Effect on Alcoholic Liver Injury in Mice"],"prefix":"10.1002","volume":"18","author":[{"given":"Xiangying","family":"Kong","sequence":"first","affiliation":[{"name":"Bioscience and Biotechnology College Shenyang Agriculture University  120 Dongling Road Shenyang 110866 P. R. 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