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These compounds were tested for its antioxidant potential, including Fe<jats:sup>3+<\/jats:sup> and Cu<jats:sup>2+<\/jats:sup> reductive ability and Fe<jats:sup>2+<\/jats:sup> chelating effects. The inhibitory effects of isolated phenolic compounds were tested towards human carbonic anhydrase I and II isoenzymes (hCA\u2005I and hCA\u2005II), butyrylcholinesterase (BChE) acetylcholinesterase (AChE), aldose reductase (AR) and \u03b1\u2010glycosidase (\u03b1\u2010gly). K<jats:sub>i<\/jats:sub> values were found these compounds in range of 0.24\u00b10.05\u20131.38\u00b10.34\u2005\u03bcM against hCA\u2005I, 0.194\u00b10.018\u20131.03\u00b10.06\u2005\u03bcM against hCA\u2005II, 0.043\u00b10.01\u20130.154\u00b10.02\u2005\u03bcM against AChE, 3.92\u00b11.08\u201311.93\u00b14.45\u2005\u03bcM against BChE, 0.082\u00b10.0008\u20131.68\u00b10.42\u2005\u03bcM against AR, and 6.93\u00b12.74\u201317.17\u00b16.70\u2005\u03bcM against \u03b1\u2010glycosidase. As a result, isolated compounds displayed inhibition effects against studied all metabolic enzymes. They are promising candidates for treating disorders like Alzheimer's disease, diabetes mellitus, glaucoma, leukemia, and epilepsy.<\/jats:p>","DOI":"10.1002\/cbdv.202200280","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T12:41:17Z","timestamp":1657197677000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Isolation of Some Phenolic Compounds from <i>Plantago subulata<\/i> L. and Determination of Their Antidiabetic, Anticholinesterase, Antiepileptic and Antioxidant Activity"],"prefix":"10.1002","volume":"19","author":[{"given":"Muhammet Serhat","family":"\u00d6zaslan","sequence":"first","affiliation":[{"name":"Department of Pharmacy Services Nihat Delibalta G\u00f6le Vocational High School Ardahan University  Ardahan 75700 Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00fcya","family":"Sa\u011flamta\u015f","sequence":"additional","affiliation":[{"name":"Central Research &amp; Application Laboratory Agri Ibrahim Cecen University  Agri Turkey"},{"name":"Medical Services and Techniques Department Vocational School of Health Services Agri Ibrahim Cecen University  Agri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3216-1098","authenticated-orcid":false,"given":"Yeliz","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services Nihat Delibalta G\u00f6le Vocational High School Ardahan University  Ardahan 75700 Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasin","family":"Gen\u00e7","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Hacettepe University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130clal","family":"Sara\u00e7o\u011flu","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Hacettepe University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130lhami","family":"G\u00fcl\u00e7in","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Atat\u00fcrk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,7]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2012.01.019"},{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","unstructured":"G. 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