{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T13:01:56Z","timestamp":1777986116706,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Ministarstvo Prosvete, Nauke i Tehnolo\u0161kog Razvoja","doi-asserted-by":"publisher","award":["451-03-68\/2022-14\/200124"],"award-info":[{"award-number":["451-03-68\/2022-14\/200124"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Ministarstvo Prosvete, Nauke i Tehnolo\u0161kog Razvoja","doi-asserted-by":"publisher","award":["451-03-68\/2022-14\/200113"],"award-info":[{"award-number":["451-03-68\/2022-14\/200113"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Essential oils obtained from different parts <jats:italic>of Achillea coarctata<\/jats:italic> species (inflorescences, stem and leaves and the whole aerial part) collected on four different locations in Serbia have been investigated to evaluate the chemical composition and antibacterial activity of isolated oils. The aim of this study was to determine differences in the chemical composition of essential oils obtained from different plant parts and how different type of substrate as well as different climate conditions affect the chemical composition of essential oils. Oxigenated terpenes were reported to be the major constituents in almost all examinated samples with 1,8\u2010cineole, caryophyllene oxide and <jats:italic>cis\u2010<\/jats:italic>cadin\u20104\u2010en\u20107\u2010ol identified as dominant compounds. Disk diffusion assay was used to determine antibacterial activity against two Gram\u2010positive (<jats:italic>Bacillus subtilis<\/jats:italic> subsp. s<jats:italic>pizizenii<\/jats:italic> ATCC 6633 and <jats:italic>Staphylococcus aureus<\/jats:italic> ATCC 6538) and three Gram\u2010negative bacteria (<jats:italic>Escherichia coli<\/jats:italic> ATCC 8739, <jats:italic>Pseudomonas aeruginosa<\/jats:italic> ATCC 9027 and <jats:italic>Salmonella abony<\/jats:italic> ATCC 6017). The obtained results showed that essential oils obtained from <jats:italic>A.\u2005coarctata<\/jats:italic> exhibit significant antibacterial activity against tested bacteria strains. The best inhibitory effect was observed against <jats:italic>S.\u2005aureus<\/jats:italic>, while on the other hand <jats:italic>P.\u2005aeruginosa<\/jats:italic> showed high level of resistance to almost all examined essential oils.<\/jats:p>","DOI":"10.1002\/cbdv.202200578","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T17:19:08Z","timestamp":1661447948000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Phytochemical Analysis and Antibacterial Activity of <i>Achillea coarctata<\/i> Poir. Essential Oils"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2679-3139","authenticated-orcid":false,"given":"Jelena G.","family":"Stamenkovi\u0107","sequence":"first","affiliation":[{"name":"Department of Chemistry Faculty of Medicine University of Ni\u0161  Blvd. Dr Zorana \u0110in\u0111ica 81 18000 Ni\u0161 Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goran M.","family":"Petrovi\u0107","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science and Mathematics University of Ni\u0161  Vi\u0161egradska 33 18000 Ni\u0161 Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra S.","family":"\u0110or\u0111evi\u0107","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science and Mathematics University of Ni\u0161  Vi\u0161egradska 33 18000 Ni\u0161 Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,20]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2013.02.006"},{"key":"e_1_2_8_2_1","first-page":"729","article-title":"\u2018Protective effect on human lymphocytes of some flavonoids isolated from two Achillea species\u2019","volume":"5","author":"Aljan\u010di\u0107 I.","year":"2010","journal-title":"Nat. Prod. Commun."},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10354-007-0431-9"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2006.03.011"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2006.05.005"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161208786404281"},{"key":"e_1_2_8_7_1","first-page":"173","article-title":"\u2018A review on phytochemistry and medicinal properties of the genus Achillea\u2019","volume":"19","author":"Saeidnia S.","year":"2011","journal-title":"DARU J. Pharm. Sci."},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.200690119"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202000097"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.14715\/cmb\/2020.66.4.13"},{"key":"e_1_2_8_11_1","unstructured":"M. Gaji\u0107 \u2018AchilleaL.In Flora Srbije 7\u2019 Josifovi\u0107 M. (Ed) Srpska akademija nauka i umetnosti Beograd 1975 p. 90\u2013109."},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/10412905.2003.9712080"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules200611432"},{"key":"e_1_2_8_14_1","first-page":"154","article-title":"\u2018Phytotoxic and Insecticidal Properties of Essential Oils and Extracts of Four Achillea Species\u2019","volume":"10","author":"Cakir A.","year":"2016","journal-title":"Rec. Nat. Prod."},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.201900484"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13596-019-00378-w"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/0972060X.2009.10643754"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/10412905.1999.9711999"},{"key":"e_1_2_8_19_1","first-page":"543","article-title":"\u2018Essential Oil Chemical Composition and Headspace Volatiles Profile of Achillea coarctata from Serbia\u2019","volume":"11","author":"Kostevski I.","year":"2016","journal-title":"Nat. Prod. 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