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The substrate concentration and presence of reduced glutathione were evaluated for their effect on the <jats:italic>in\u2005vitro<\/jats:italic> inhibition of the GL enzyme. Assays were also performed in the presence and absence of simulated gastric fluid. The antidiabetic fractions 2 and 3 were the most inhibited GL, but their activity were significantly decreased in the presence of gastric fluid. Chromatographic analyses confirmed the predominant presence of VEB in the samples. The samples had VEB concentrations between 49.9 and 243.5\u2005mg\/g. Simulation of the molecular docking of VEB were consistent with its GL\u2010inhibitory activity. It can conclude that the crude ethanol extract and fractions show inhibitory activity against the GL enzyme.<\/jats:p>","DOI":"10.1002\/cbdv.202200760","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T02:53:50Z","timestamp":1674615230000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Inhibition of \u03b1\u2010Glycosidase by <i>Lippia dulcis<\/i> Trevir. 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