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Moreover, the effects of EO in combination with ampicillin and tetracycline were investigated. Thirty\u2010four components, mainly mono\u2010and sesquiterpenes that represented 94.05\u2009% of the chemical composition, were identified in the EO. The EO showed bacteriostatic and bactericidal activities against all strains tested. Furthermore, the EO showed a synergistic effect with ampicillin and tetracycline. EO significantly inhibited biofilm formation and reduced the number of viable cells in biofilms. The EO may be a promising natural product for preventing bacterial biofilm infections.<\/jats:p>","DOI":"10.1002\/cbdv.202200777","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T13:43:42Z","timestamp":1671630222000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Chemical Composition Determination and Evaluation of the Antimicrobial Activity of Essential Oil from <i>Croton blanchetianus<\/i> (Euphorbiaceae) against Clinically Relevant Bacteria"],"prefix":"10.1002","volume":"20","author":[{"given":"Aluska Kelly A.","family":"Nunes","sequence":"first","affiliation":[{"name":"Faculdade de Ci\u00eancias Exatas e Naturais Universidade do Estado do Rio Grande do Norte  Mossor\u00f3 RN Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen","family":"Ara\u00fajo Malveira","sequence":"additional","affiliation":[{"name":"Departamento de Bioqu\u00edmica e Biologia Molecular Universidade Federal do Cear\u00e1  Fortaleza CE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Lopes Andrade","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Integrado de Biomol\u00e9culas Departamento de Patologia e Medicina Legal Universidade Federal do Cear\u00e1  Fortaleza CE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wildson Max","family":"Barbosa da Silva","sequence":"additional","affiliation":[{"name":"Universidade Estadual do Cear\u00e1, Centro de Ci\u00eancia e Tecnologia, Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias Naturais  Fortaleza CE Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selene Maia","family":"de Morais","sequence":"additional","affiliation":[{"name":"Universidade Estadual do Cear\u00e1, Centro de Ci\u00eancia e Tecnologia, Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias Naturais  Fortaleza CE Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9lcio","family":"Silva dos Santos","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Integrado de Biomol\u00e9culas Departamento de Patologia e Medicina Legal Universidade Federal do Cear\u00e1  Fortaleza CE Brazil"},{"name":"Universidade Estadual do Vale do Acara\u00fa, Centro de Ci\u00eancias Exatas e Tecnologia  Sobral CE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Cavalcanti de Albuquerque","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias Exatas e Naturais Universidade do Estado do Rio Grande do Norte  Mossor\u00f3 RN Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edson","family":"Holanda Teixeira","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Integrado de Biomol\u00e9culas Departamento de Patologia e Medicina Legal Universidade Federal do Cear\u00e1  Fortaleza CE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego Nathan","family":"do Nascimento Souza","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias Exatas e Naturais Universidade do Estado do Rio Grande do Norte  Mossor\u00f3 RN Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8538-5015","authenticated-orcid":false,"given":"Mayron","family":"Alves de Vasconcelos","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias Exatas e Naturais Universidade do Estado do Rio Grande do Norte  Mossor\u00f3 RN Brazil"},{"name":"Universidade do Estado de Minas Gerais, Unidade de Divin\u00f3polis  Divin\u00f3polis MG Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,21]]},"reference":[{"key":"e_1_2_9_1_1","first-page":"31","article-title":"\u2018Evaluation of biotechnological potential of Aspergillus parasiticus UCP 1281 in the wastewater biotreatment of dairy industry and lipids production\u2019","volume":"8","author":"Reis R. 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