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Different parts of <jats:italic>R. apiculata<\/jats:italic>, an abundant mangrove found in Bhitarkanika National Park, India were extracted with methanol and a mixture of solvents methanol\/ethanol\/chloroform (60\u2009:\u200920\u2009:\u200920) to evaluate their antimicrobial properties. The combination solvent extract of bark had the highest zone of inhibition (ZOI) of 18.62\u2005mm against <jats:italic>Pseudomonas aeruginosa<\/jats:italic> and a ZOI of 17.41\u2005mm against <jats:italic>Streptococcus mitis<\/jats:italic>. Bark extracts had the highest DPPH (43\u2009%) and FRAP (96\u2009%) activities. The combination solvent bark extract of <jats:italic>R. apiculata<\/jats:italic> had the highest ZOI of 20.42\u2005mm (lowest MIC of 2.12\u2005\u03bcg\/ml) against <jats:italic>Candida albicans<\/jats:italic> and ZOI of 15.33\u2005mm (MIC of 3.02\u2005\u03bcg\/mL) against <jats:italic>Penicillium chrysogenum<\/jats:italic>. Combination bark extracts of <jats:italic>R. apiculata<\/jats:italic> contained flavanols than methanolic extracts. The crude extract of <jats:italic>R. apiculata<\/jats:italic> bark made with a mixture of solvents containing more active ingredients could be used in novel drug formulation.<\/jats:p>","DOI":"10.1002\/cbdv.202201144","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T19:34:41Z","timestamp":1689881681000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Antimicrobial and Antioxidant Property of a True Mangrove <i>Rhizophora apiculata<\/i> Bl."],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6095-4840","authenticated-orcid":false,"given":"Srinivas","family":"Acharya","sequence":"first","affiliation":[{"name":"Department of Botany Utkal University  Bhubaneswar 751004 Odisha India"},{"name":"Department of Environmental Science Government Autonomous College  Phulbani, Kandhamal 762001 Odisha India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8968-7483","authenticated-orcid":false,"given":"Pallavi","family":"Jali","sequence":"additional","affiliation":[{"name":"Department of Botany Utkal University  Bhubaneswar 751004 Odisha India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9328-3622","authenticated-orcid":false,"given":"Madhusmita","family":"Pradhan","sequence":"additional","affiliation":[{"name":"Majhighariani Institute of Technology and Science  Rayagada 765017 Odisha India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0826-9608","authenticated-orcid":false,"given":"Chinmay","family":"Pradhan","sequence":"additional","affiliation":[{"name":"Department of Botany Utkal University  Bhubaneswar 751004 Odisha India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7435-7983","authenticated-orcid":false,"given":"Pradipta K.","family":"Mohapatra","sequence":"additional","affiliation":[{"name":"Department of Botany Ravenshaw University  Cuttack 753003 Odisha India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,9]]},"reference":[{"key":"e_1_2_10_1_1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.phyplu.2021.100107","volume":"1","author":"Mitra S.","year":"2021","journal-title":"Phytomedicine Plus"},{"key":"e_1_2_10_2_1","first-page":"1","volume":"3","author":"Upadhyay V. 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