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Bioassays revealed that compounds <jats:bold>1\u20139<\/jats:bold> were specifically immunosuppressive to T lymphocytes with IC<jats:sub>50<\/jats:sub> values ranging from 0.41 to 9.4\u2005\u03bcM, of which compounds <jats:bold>1<\/jats:bold> (IC<jats:sub>50<\/jats:sub>=1.62\u2005\u03bcM) and <jats:bold>2<\/jats:bold> (IC<jats:sub>50<\/jats:sub>=0.41\u2005\u03bcM) were promising immunosuppressive agents for T lymphocytes with the selectivity indices of 19.9 and 79.5, respectively.<\/jats:p>","DOI":"10.1002\/cbdv.202201185","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T15:04:22Z","timestamp":1676559862000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Immunosuppressive Bibenzyl\u2010phenylpropane Hybrids from <i>Dendrobium devonianum<\/i>"],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0131-4197","authenticated-orcid":false,"given":"Rui","family":"Zhan","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering Yunnan Normal University  Kunming 650050 P. 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