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The IC<jats:sub>50<\/jats:sub> values of K\u201022 on cancer cell lines range from 0.797 \u03bcg\/mL to 3.426\u2005\u03bcg\/mL, indicating that K\u201022 might preferably inhibit A549, Saos\u20102, MCF\u20107, and HT\u201029 cell proliferation and thus have better therapeutic activity. Furthermore, K\u201022 stimulated apoptosis via up\u2010regulation of the mRNA and protein expression level of Bax\/Bcl\u20102 ratio in A549, Saos\u20102, MCF\u20107, and HT\u201029. K\u201022 exhibited antimicrobial activity against <jats:italic>S.\u2005aureus<\/jats:italic>, <jats:italic>E.\u2005faecalis<\/jats:italic>, <jats:italic>K.\u2005pneumonia<\/jats:italic>, <jats:italic>P.\u2005aeruginosa<\/jats:italic>, <jats:italic>C.\u2005utilis<\/jats:italic>, and <jats:italic>C.\u2005albicans<\/jats:italic>. Experimental results show that the compound has inhibitory potential with an IC<jats:sub>50<\/jats:sub> value of 178.10\u2005\u03bcM for the BChE (butyrylcholinesterase) enzyme, which has a vital role in the progression of Alzheimer's disease. As a result, compound K\u201022 exhibits a strong potential for medical use due to its anticancer, antibacterial, antifungal, and anti\u2010Alzheimer properties.<\/jats:p>","DOI":"10.1002\/cbdv.202300038","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T19:46:06Z","timestamp":1682711166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Silver Compound with Potential Applications as an Anticancer, Antibacterial, Antifungal, and Anti\u2010Alzheimer's Agent"],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7896-1042","authenticated-orcid":false,"given":"Nesrin","family":"Korkmaz","sequence":"first","affiliation":[{"name":"Department of Basic Sciences and Health Hemp Institute Yozgat Bozok University  Yozgat Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dursun","family":"K\u0131sa","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Genetics Faculty of Science Bartin University  Bartin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Department of Genetics and Bioengineering Rafet Kay\u0131\u015f Faculty of Engineering Alanya Alaaddin Keykubat University  Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazan G\u00f6k\u015fen","family":"Tosun","sequence":"additional","affiliation":[{"name":"Department of Medical Services and Techniques Tokat Vocational School of Health Services Tokat Gaziosmanpa\u015fa University  Tokat Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aykut","family":"\u00d6zg\u00fcr","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Laboratory and Veterinary Health Program Artova Vocational School Tokat Gaziosmanpa\u015fa University  Tokat Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rizvan","family":"Imamo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Genetics Faculty of Science Bartin University  Bartin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Karada\u011f","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Arts and Sciences Yozgat Bozok University  Yozgat Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,19]]},"reference":[{"key":"e_1_2_8_1_1","first-page":"1","author":"G\u00f6k\u015fen Tosun N.","year":"2022","journal-title":"Inorg. 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