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The present results show that the methanol\u2010dichloromethane (1\u2009:\u20091, <jats:italic>v\/v<\/jats:italic>) solvent system is the most efficient solvent system for the extraction of ursolic acid from the plant sample with the highest yield (2.22\u2005g\/100\u2005g plant sample). In the present study, a new practical method for the isolation of ursolic acid from polar extracts was also demonstrated for the first time. The inhibition effects of the extracts and ursolic acid were also revealed on <jats:italic>\u03b1<\/jats:italic>\u2010glycosidase, acetylcholinesterase, butyrylcholinesterase, and human carbonic anhydrase I and II enzymes by determining IC<jats:sub>50<\/jats:sub> values for the first time. The extracts and ursolic acid acted as potent antidiabetic agents by strongly inhibiting the <jats:italic>\u03b1<\/jats:italic>\u2010glycosidase activity, whereas they were found to be very weak neuroprotective agents. In view of the present results, <jats:italic>L. stoechas<\/jats:italic> and its major metabolite, ursolic acid, can be recommended as a herbal source to control postprandial blood sugar levels and prevent diabetes by delaying the digestion of starch in food.<\/jats:p>","DOI":"10.1002\/cbdv.202300414","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T12:04:34Z","timestamp":1687262674000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["<i>Lavandula stoechas<\/i> L. subsp. <i>stoechas<\/i>, a New Herbal Source for Ursolic Acid: Quantitative Analysis, Purification and Bioactivity Studies"],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7653-6480","authenticated-orcid":false,"given":"Tuba","family":"Aydin","sequence":"first","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy A\u011fr\u0131 \u0130brahim \u00c7e\u00e7en University  Agri 04100 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4400-2302","authenticated-orcid":false,"given":"Ruya","family":"Saglamtas","sequence":"additional","affiliation":[{"name":"Vocational School of Health Services A\u011fr\u0131 \u0130brahim \u00c7e\u00e7en University  Agri 04100 T\u00fcrkiye"},{"name":"Central Research and Application Laboratory A\u011fr\u0131 \u0130brahim \u00c7e\u00e7en University  Agri 04100 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4846-5398","authenticated-orcid":false,"given":"Mehmet","family":"Gumustas","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Department Ba\u015fak\u015fehir \u00c7am and Sakura City Hospital  Istanbul 34000 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9339-9334","authenticated-orcid":false,"given":"Mucip","family":"Genisel","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany Faculty of Pharmacy A\u011fr\u0131 \u0130brahim \u00c7e\u00e7en University  Agri 04100 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cavit","family":"Kazaz","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Atat\u00fcrk University  Erzurum 25000 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Cakir","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Science Kilis 7 Aral\u0131k University  Kilis 79000 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,19]]},"reference":[{"key":"e_1_2_9_1_1","first-page":"1","volume":"2019","author":"Canli K.","year":"2009","journal-title":"Adv. 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