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In this context, the use of plant extracts constitutes an alternative to avoid this kind of contaminants. In this work, we investigated the chemical constituents and insecticidal activity of different extracts of leaves and stems of <jats:italic>Argemone ochroleuca<\/jats:italic> Sweet (Papaveraceae) against three economically important pests <jats:italic>Sitophilos zeamais<\/jats:italic> (Coleoptera:Curculionidae), <jats:italic>Galleria mellonella<\/jats:italic> (Lepidoptera:Pyralidae) and <jats:italic>Xyleborus ferrugineus<\/jats:italic> (Coleoptera:Scolytidae). A GC\u2010MS analysis mostly revealed the presence benzylisoquinoline alkaloids such as allocryptopine, protopine, among others. For the insecticidal activity, after nine hours of contact, the methanolic leaves extract showed a 100\u2009% of mortality, followed by the dichloromethane stems extract with up to 93\u2009% of mortality. The results suggest that the benzylisoquinoline alkaloids are involved in the insecticidal activity through the octopaminergic system of the tested insects.<\/jats:p>","DOI":"10.1002\/cbdv.202301279","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T23:49:45Z","timestamp":1704757785000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Metabolomic Approaches in Assessing the Insecticidal Activity of the Extracts from <i>Argemone ochroleuca<\/i> Sweet (Papaveraceae) Against Three Diverse Crop Pests of Economic Importance"],"prefix":"10.1002","volume":"21","author":[{"given":"Alfonso","family":"Reyes\u2010Luna","sequence":"first","affiliation":[{"name":"Departamento de Qu\u00edmica Divisi\u00f3n de Ciencias Naturales y Exactas Universidad de Guanajuato  Noria Alta S\/N Guanajuato Gto. 36050"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunice","family":"Y\u00e1\u00f1ez\u2010Barrientos","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Divisi\u00f3n de Ciencias Naturales y Exactas Universidad de Guanajuato  Noria Alta S\/N Guanajuato Gto. 36050"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xochitl N.","family":"Alba\u2010Mares","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Divisi\u00f3n de Ciencias Naturales y Exactas Universidad de Guanajuato  Noria Alta S\/N Guanajuato Gto. 36050"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Luis Olivares\u2010Romero","sequence":"additional","affiliation":[{"name":"Red de Estudios Moleculares Avanzados Instituto de Ecolog\u00eda AC  Carretera Antigua a Coatepec 351, El Haya Xalapa Ver. 91070, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngel","family":"Josabad Alonso\u2010Castro","sequence":"additional","affiliation":[{"name":"Departamento de Farmacia Divisi\u00f3n de Ciencias Naturales y Exactas Universidad de Guanajuato  Noria Alta S\/N Guanajuato Gto. 36050, M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Cruz Cruz","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Divisi\u00f3n de Ciencias Naturales y Exactas Universidad de Guanajuato  Noria Alta S\/N Guanajuato Gto. 36050"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarisa","family":"Villegas G\u00f3mez","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Divisi\u00f3n de Ciencias Naturales y Exactas Universidad de Guanajuato  Noria Alta S\/N Guanajuato Gto. 36050"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,22]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-10-8687-8_3"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2134\/agronmonogr18.3ed.c13"},{"key":"e_1_2_9_3_1","first-page":"803","volume":"10","author":"Hern\u00e1ndez-Trejo A.","year":"2019","journal-title":"Rev. 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