{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T07:36:37Z","timestamp":1776497797689,"version":"3.51.2"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:00:00Z","timestamp":1708473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective<\/jats:bold>: To study the antibacterial and phytochemical activities of bioactive elements in the leaves of <jats:italic>Annona reticulata<\/jats:italic> Linn, a historically used Bangladeshi medicinal plant. <jats:bold>Methods<\/jats:bold>: Shade\u2010dried and crushed plant leaves were soaked with various solvents to obtain samples for different chemical analyses. All extracts were selected for antimicrobial, physicochemical, and Pharmacological investigations. The antimicrobial activity was evaluated using disc diffusion assay, and broth microdilution methods determined potentiation of the activities of the antibiotic antibacterial activity of the plant extracts was investigated using either gram\u2010positive or gram\u2010negative pathogenic wild\u2010type bacteria. <jats:bold>Results<\/jats:bold>: From the initial phytochemical and pharmacological studies, it was clear that all extracts, methanol, chloroform, and ethyl acetate, of the leaves of <jats:italic>A. reticulata<\/jats:italic>, were proven to process potent bioactive constituents. While differential antimicrobial properties were found to be possessed by all extracts, methanolic extract was the most potent one against all tested microorganisms. It also has potentiated the activities of antibiotics in <jats:italic>E. coli<\/jats:italic>. <jats:bold>Conclusion<\/jats:bold>: Bioactive constituents in the plant extracts were shown to possess phytochemical and antimicrobial activities. More investigation is needed to segregate the chemical components responsible for the respective phytochemical and antimicrobial activities.<\/jats:p>","DOI":"10.1002\/cbdv.202301495","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T07:09:47Z","timestamp":1706512187000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Unveiling Annona Reticulata's Bioactive Arsenal for Enhanced Antibiotic Effects"],"prefix":"10.1002","volume":"21","author":[{"given":"Muhammad","family":"Ramiz Uddin","sequence":"first","affiliation":[{"name":"Department of Pharmacy Jahangirnagar University, Savar  Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5529-8893","authenticated-orcid":false,"given":"Asif","family":"Shahriar","sequence":"additional","affiliation":[{"name":"Department of Microbiology Stamford University Bangladesh  51 Siddeswari Road Dhaka 1217 Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halima","family":"Jahan Mim","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Jahangirnagar University, Savar  Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bibi","family":"Khadiza Papia","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Jahangirnagar University, Savar  Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohd. 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Q Khan","sequence":"additional","affiliation":[{"name":"Department of Applied Chemistry and Chemical Engineering University of Dhaka  Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahatul","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Genetic Engineering and Biotechnology Shahjalal University of Science and Technology  Sylhet Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nour","family":"Fatema","sequence":"additional","affiliation":[{"name":"Department of Microbiology Stamford University Bangladesh  51 Siddeswari Road Dhaka 1217 Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anwar","family":"Parvez","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Faculty of Allied Health Sciences Daffodil International University  Dhaka 1207 Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goutam","family":"Kumar Roy","sequence":"additional","affiliation":[{"name":"Department of Fisheries  Kushtia Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohel","family":"Rana","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Jahangirnagar University, Savar  Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,21]]},"reference":[{"key":"e_1_2_11_1_1","doi-asserted-by":"publisher","DOI":"10.4103\/2231-4040.104709"},{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19031864"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2013.02.008"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.6b00167"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b00453"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2020.129546"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.2c00263"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568026013395605"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.1c00100"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2008.12.011"},{"key":"e_1_2_11_11_1","doi-asserted-by":"crossref","unstructured":"A.\u2005G. 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