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The influence of several parameters such as type of solvent (50% acetone, 50% methanol, 50% ethanol, and water), solvent concentration (30\u2010100%; v\/v), solvent acidity (0\u20100,1 N), temperature (20\u00b0C\u201340\u00b0C) and time (30\u2013360\u00a0min) on the yield extraction of total phenolic content (TPC), total flavonoid content (TFC), total proanthocyanidin content (TPAC), and on the antioxidant activity: DPPH\u2010radical scavenging activity (DPPH\u2010RSA), ABTS\u2010radical scavenging activity (ABTS\u2010RSA) and ferric reducing power (FRP) was studied. The results showed that 50% acetone, 40\u00b0C, and 180\u00a0min were the best conditions for extracting TPC (87\u00a0mg GAE\/g DW), TFC (12\u00a0mg QE\/g DW), and TPAC (76\u00a0mg CE\/g DW). Myrtle berries extracted with these conditions also exhibited the strongest antioxidant activity: DPPH\u2010RSA (143 mg TE\/g DW), ABTS\u2010RSA (164\u00a0mg TE\/g DW), and FRP (69\u00a0mg AAE\/g DW). Pearson correlation coefficients showed good positive correlations between TPC, TFC, and TPAC and antioxidant activities (DPPH\u2010RSA, ABTS\u2010RSA, and FRP), mainly under the effect of solvent type (0.93\u00a0&lt;\u00a0r\u00a0&lt;\u00a00.99) and solvent concentration (0.91\u00a0&lt;\u00a0r\u00a0&lt;\u00a00.99).<\/jats:p>","DOI":"10.1002\/cbdv.202301675","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T09:30:02Z","timestamp":1732095002000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Optimization of Extraction Conditions of Phenolic Compounds and Antioxidant Activity From Myrtle (<i>Myrtus communis<\/i> L.) 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