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The ethyl acetate fraction (EAF) exhibited potent antifungal activity against <jats:italic>Candida<\/jats:italic> spp (1.95\u20133.90\u2005\u03bcg\u2009mL<jats:sup>\u22121<\/jats:sup>) and potent antioxidant activity in the DPPH (1.74\u00b10.07\u2005\u03bcg\u2009mL<jats:sup>\u22121<\/jats:sup>), FRAP (654.01\u00b142.09\u2005\u03bcmol E<jats:sub>Trolox<\/jats:sub>\/g<jats:sub>sample<\/jats:sub>), and ORAC (3698.88\u00b137.28\u2005\u03bcmol E<jats:sub>Trolox<\/jats:sub>\/g<jats:sub>sample<\/jats:sub>) methods. The EE displayed inhibition against the \u03b1\u2010amylase enzyme (8.42\u00b10.05\u2005\u03bcg\u2009mL<jats:sup>\u22121<\/jats:sup>). Flavonoids, hydrolysable tannins, triterpenoids, and phenolic acids, identified in the EE and fractions via (\u2212)\u2010HPLC\u2010ESI\u2010MS\/MS analysis, were found to contribute to the species\u2032 biological activity potentially. These findings suggest promising avenues for further research and potential applications in pharmacology and natural products, offering new possibilities in the fight against global health issues.<\/jats:p>","DOI":"10.1002\/cbdv.202400680","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T17:14:47Z","timestamp":1715793287000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Chemical Composition of Extracts and Fractions from <i>Miconia Ibaguensis<\/i> (Melastomataceae) Leaves and Evaluation of Biological Activities"],"prefix":"10.1002","volume":"21","author":[{"given":"Gabriela S.","family":"Sehnem","sequence":"first","affiliation":[{"name":"Nucleus of Research in Natural Products, Institute of Chemistry Federal University of Uberl\u00e2ndia \u2013  MG Uberl\u00e2ndia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2709-230X","authenticated-orcid":false,"given":"Julia A.","family":"Silva","sequence":"additional","affiliation":[{"name":"Nucleus of Research in Natural Products, Institute of Chemistry Federal University of Uberl\u00e2ndia \u2013  MG Uberl\u00e2ndia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0370-8405","authenticated-orcid":false,"given":"Tiara","family":"da C. 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