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Recent studies have identified alkaloids, saponins, terpenes, phenols, flavonoids, and other compounds in the plant, all of which demonstrate significant pharmacological effects such as anti\u2010inflammatory and anti\u2010tumor properties. While currently valued for its use in wetland plant landscapes and as a garden design color enhancer, ongoing research on the chemical composition and pharmacological properties of <jats:italic>Hylomecon japonica<\/jats:italic> is uncovering its potential medical applications. This paper provides a comprehensive review of extraction and separation methods, chemical components, and pharmacological activities of these compounds to further explore the medicinal potential of <jats:italic>Hylomecon japonica<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/cbdv.202400815","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T13:27:06Z","timestamp":1721827626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chemical Constituents and Biological Activities of the <i>Hylomecon japonica<\/i> (Thunb.) Prantl &amp; K\u00fcndig \u2013 A Comprehensive Review"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0121-3369","authenticated-orcid":false,"given":"Mengmeng","family":"Wang","sequence":"first","affiliation":[{"name":"Development and Utilization Key Laboratory of Northeast Plant Materials, School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University  Shenyang 110016 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peixin","family":"Shi","sequence":"additional","affiliation":[{"name":"Development and Utilization Key Laboratory of Northeast Plant Materials, School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University  Shenyang 110016 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Zhang","sequence":"additional","affiliation":[{"name":"Development and Utilization Key Laboratory of Northeast Plant Materials, School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University  Shenyang 110016 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7142-0186","authenticated-orcid":false,"given":"Na","family":"Han","sequence":"additional","affiliation":[{"name":"College of Chinese Meteria Medica Shenyang Pharmaceutical University  103, Wenhua Road Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"e_1_2_12_1_1","first-page":"9","volume":"63","author":"Long F.","year":"2017","journal-title":"Shaanxi J. 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