{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:34:08Z","timestamp":1790818448637,"version":"4.1.0"},"reference-count":83,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Stachys maritima<\/jats:italic> is a species of plant belonging to the Lamiaceae, commonly known as common sea lavender. The extraction of <jats:italic>S. maritima<\/jats:italic> involves drying the aerial parts, grinding them into powder, followed by extraction with methanol. ST\u2010CQDs (<jats:italic>S. maritima<\/jats:italic> carbon quantum dots) were synthesized from <jats:italic>S. maritima<\/jats:italic> extract via pyrolysis. An optimal synthesis condition of 7\u2005hours of pyrolysis was determined to yield ST\u2010CQDs with high absorption in the visible\u2010UV range. Characterization techniques such as UV\u2010visible spectroscopy and TEM (Transmission Electron Microscopy) confirmed the spherical and homogeneous nature of the carbon quantum dots. <jats:italic>S. maritima<\/jats:italic> methanol extract exhibited strong antioxidant activity with a DPPH (2,2\u2010Diphenyl\u20101\u2010picrylhydrazyl) IC<jats:sub>50<\/jats:sub> value of 0.114\u00b10.001\u2005mg\/mL. Similarly, ST\u2010CQDs showed strong antioxidant properties with a DPPH IC<jats:sub>50<\/jats:sub> value of 0.69\u00b10.03\u2005mg\/mL. Moreover, the methanol extract of <jats:italic>S. maritima<\/jats:italic> demonstrated antimicrobial activity against <jats:italic>E. coli<\/jats:italic> ATCC 25922 and <jats:italic>S. aureus<\/jats:italic> ATCC 25923, with effective MIC values of 25\u2005mg\/mL and 6.25\u2005mg\/mL, respectively. However, ST\u2010CQDs did not show antimicrobial effects against the tested microorganisms (<jats:italic>E. coli<\/jats:italic> ATCC 25922, <jats:italic>S. aureus<\/jats:italic> ATCC 25923, <jats:italic>K. pneumoniae<\/jats:italic> ATCC 13883, and <jats:italic>C. albicans<\/jats:italic> ATCC 10231). Molecular docking simulations suggested that compounds derived from <jats:italic>S. maritima<\/jats:italic> (such as 9,12,15\u2010octadecatrienoic acid and palmitic acid) could interact effectively with TNF\u2010\u03b1 (Tumor Necrosis Factor Alpha), indicating potential anti\u2010inflammatory properties. This study highlights that the methanol extract of <jats:italic>S. maritima<\/jats:italic> possesses potent antioxidant and antimicrobial activities, and ST\u2010CQDs exhibit similar antioxidant properties. However, ST\u2010CQDs did not demonstrate antimicrobial activity against the tested pathogens. Molecular docking simulations also suggest potential anti\u2010inflammatory properties of compounds derived from the plant.<\/jats:p>","DOI":"10.1002\/cbdv.202401057","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T16:09:19Z","timestamp":1720800559000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Antioxidant and Antimicrobial Properties of <i>Stachys maritima<\/i> via Quantum Dots and Molecular Docking"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6045-0183","authenticated-orcid":false,"given":"Erdi","family":"Can Aytar","sequence":"first","affiliation":[{"name":"Department of Horticulture Faculty of Agriculture Usak University  U\u015fak 64200 T\u00fcrkiy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,4]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2021.11.031"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-64179-3.00003-7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-2863(02)00208-5"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7431439"},{"key":"e_1_2_8_5_1","first-page":"1","volume":"3","author":"Joshi B.","year":"2011","journal-title":"J. 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