{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:07:17Z","timestamp":1753862837967,"version":"3.41.2"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31900285"],"award-info":[{"award-number":["31900285"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Eighteen aromatic abietane\u2010type diterpenes, including three previously unreported compounds, Salkanoids A\u2212C (<jats:bold>1<\/jats:bold>\u2013<jats:bold>3<\/jats:bold>), were isolated from the roots of <jats:italic>Salvia prattii<\/jats:italic>. Their stuctures were extensively elucidated using 1D\/2D NMR, high\u2010resolution electrospray ionization mass spectrometry (HRESIMS) data, and ECD calculation. Among these, compounds <jats:bold>1<\/jats:bold>, <jats:bold>6<\/jats:bold> and <jats:bold>7<\/jats:bold> belong to a class of diterpenes featuring a [5, 5]\u2010oxaspirolactones moiety, a rare structure isolated from the <jats:italic>Salvia<\/jats:italic> plants. All the isolates were assessed for their protective effects against alcoholic liver disease using ethanol\u2010induced AML\u201012\u2005cell lines. The findings revealed that compounds <jats:bold>2<\/jats:bold>, <jats:bold>5<\/jats:bold>, <jats:bold>8<\/jats:bold> and <jats:bold>15<\/jats:bold> demonstrated potential protective activity.<\/jats:p>","DOI":"10.1002\/cbdv.202401339","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T09:32:33Z","timestamp":1727256753000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Aromatic Abietane\u2010Type Diterpenoids from the Roots of <i>Salvia prattii<\/i> and their Protective Activity Against Alcoholic Liver Disease"],"prefix":"10.1002","volume":"22","author":[{"given":"Ming","family":"Zhang","sequence":"first","affiliation":[{"name":"Anhui Provincial Laboratory of Inflammatory and Immunity Disease Anhui Institute of Innovative Drugs School of pharmacy Anhui Medical University  Hefei 230032 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010Ran","family":"Yang","sequence":"additional","affiliation":[{"name":"Anhui Provincial Laboratory of Inflammatory and Immunity Disease Anhui Institute of Innovative Drugs School of pharmacy Anhui Medical University  Hefei 230032 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan\u2010Fang","family":"Chen","sequence":"additional","affiliation":[{"name":"Anhui Provincial Laboratory of Inflammatory and Immunity Disease Anhui Institute of Innovative Drugs School of pharmacy Anhui Medical University  Hefei 230032 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fu\u2010Cai","family":"Ren","sequence":"additional","affiliation":[{"name":"Anhui Provincial Laboratory of Inflammatory and Immunity Disease Anhui Institute of Innovative Drugs School of pharmacy Anhui Medical University  Hefei 230032 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang\u2010Dong","family":"Pu","sequence":"additional","affiliation":[{"name":"Anhui Provincial Laboratory of Inflammatory and Immunity Disease Anhui Institute of Innovative Drugs School of pharmacy Anhui Medical University  Hefei 230032 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6896-4541","authenticated-orcid":false,"given":"Chuan\u2010Pu","family":"Shen","sequence":"additional","affiliation":[{"name":"Anhui Provincial Laboratory of Inflammatory and Immunity Disease Anhui Institute of Innovative Drugs School of pharmacy Anhui Medical University  Hefei 230032 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,4]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr200058f"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2023.106834"},{"key":"e_1_2_9_3_1","first-page":"1177","volume":"12","author":"Kawabe H.","year":"2017","journal-title":"Nat. Prod. Commun."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2021.11.012"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.593"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13642"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2023.113819"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2020.104521"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2014.01.001"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/07352689.2021.1935719"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA02022B"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2014.07.001"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(00)83136-2"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1246\/cl.1990.1885"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6OB00139D"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(83)80033-8"},{"key":"e_1_2_9_17_1","first-page":"1","author":"Qian S.","year":"2023","journal-title":"Nat. Prod. Res."},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hlca.200490210"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(88)80134-1"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2012.09.055"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)86225-6"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.0c01256"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/10286020902877754"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202401339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T17:42:37Z","timestamp":1737135757000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202401339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,4]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1002\/cbdv.202401339"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202401339","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"type":"print","value":"1612-1872"},{"type":"electronic","value":"1612-1880"}],"subject":[],"published":{"date-parts":[[2024,11,4]]},"assertion":[{"value":"2024-05-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202401339"}}