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The objective of this study was to ascertain the antioxidant, tyrosinase, and collagenase inhibitory activities and to analyse the volatile oil and extracts derived from <jats:italic>E. chrysantha<\/jats:italic> using GC\/MS\/SPME. The antioxidant and enzyme inhibition activities were evaluated using spectrophotometric methods. The findings indicated that the methanol extract of <jats:italic>E. chrysantha<\/jats:italic> exhibited the highest antioxidant activity. Furthermore, both the methanol extract and volatile oil of the plant demonstrated potent inhibitory effects on tyrosinase and collagenase. A total of 84 volatile compounds were identified from the hydrodistilled oil obtained using a microwave oven, and 23 compounds were detected by the solid\u2010phase microextraction (SPME) method. The most frequently occurring volatile components were <jats:italic>\u03b1<\/jats:italic>\u2010Phellandrene, <jats:italic>o<\/jats:italic>\u2010Cymene, <jats:italic>p<\/jats:italic>\u2010Cymene, E\u2010<jats:italic>\u03b2<\/jats:italic>\u2010Farnesene, Carotol, trans\u2010Caryophyllene, and <jats:italic>\u03b2<\/jats:italic>\u2010Phellandrene. The results of this study indicate that <jats:italic>E. chrysantha<\/jats:italic> has the potential to be developed for the treatment of hyperpigmentation issues and anti\u2010aging applications. Furthermore, it may also have applications in pharmacology, cosmetics and the food industry.<\/jats:p>","DOI":"10.1002\/cbdv.202401366","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T10:58:05Z","timestamp":1727693885000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Investigation of Antioxidant and Enzyme Inhibitory Activities of <i>Echinophora chrysantha<\/i>: Microwave\u2010Assisted Hydrodistillation and SPME Analysis of its Essential Oils"],"prefix":"10.1002","volume":"22","author":[{"given":"Osman","family":"\u015eahin","sequence":"first","affiliation":[{"name":"Department of Biochemistry Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4401-8073","authenticated-orcid":false,"given":"\u015eeyda","family":"Kanbolat","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nevin Ula\u015f","family":"\u00c7olak","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merve","family":"Badem","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu\u011fba","family":"Suba\u015f","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u0131la \u00d6zlem","family":"\u015eener","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Gulhane Faculty of Pharmacy University of Health Sciences  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuriye","family":"Korkmaz","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atila Taner","family":"Kalayc\u0131o\u011flu","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Microbiology Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erg\u00fcn","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alperen \u00dcmit","family":"Say\u0131m","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rezzan","family":"Aliyaz\u0131c\u0131o\u011flu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ufuk","family":"\u00d6zgen","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy Faculty of Pharmacy Karadeniz Technical University  Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Kandemir","sequence":"additional","affiliation":[{"name":"Department of Biology Faculty of Science Erzincan University  Erzincan Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"e_1_2_9_1_1","first-page":"77","volume":"16","author":"K\u0131rba\u011f S.","year":"2006","journal-title":"YYU. 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