{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:35:42Z","timestamp":1786977342783,"version":"build-2736575974"},"reference-count":88,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T00:00:00Z","timestamp":1730073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T00:00:00Z","timestamp":1730073600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Anogeissus latifolia<\/jats:italic>\n                    , commonly known as Axlewood, Indian Gum Tree, or Gum Ghatti, belongs to the Combretaceae family and is native to India, Nepal, Myanmar, and Sri Lanka. It thrives in most tropical and subtropical regions of India. Different parts of the plant contain various proteins, carbohydrates, sugars (arabinose, galactose, mannose, xylose, rhamnose, and glucuronic acid), minerals (magnesium and calcium salts of ghattic acid), and a wide range of phytochemicals such as alkaloids, flavonoids, phenols, terpenoids, sterols, saponins, tannins, coumarins, quinine, and ellagic acid. Studies have indicated the potential of\n                    <jats:italic>Anogeissus latifolia<\/jats:italic>\n                    in managing various health conditions, including antimicrobial, anti\u2010inflammatory, anti\u2010diabetic, anti\u2010parasitic, antioxidant, hepatoprotective, wound healing, and hypolipidemic effects. However, like many medicinal plants,\n                    <jats:italic>Anogeissus latifolia<\/jats:italic>\n                    demonstrates a dose\u2010dependent toxicity profile, particularly when administered intraperitoneally. Research efforts have been directed towards elucidating its safety profile, and findings suggest that it can be considered safe when administered within prescribed dosages. This paper aims to provide a comprehensive review encompassing the ethnobotanical significance, morphological characteristics, phytochemistry, pharmacological actions, and toxicological aspects of\n                    <jats:italic>Anogeissus latifolia<\/jats:italic>\n                    . Additionally, it explores future research perspectives in the field of\n                    <jats:italic>Anogeissus latifolia<\/jats:italic>\n                    pharmacology and therapeutics.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202401378","type":"journal-article","created":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T13:10:06Z","timestamp":1724850606000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["<i>Anogeissus Latifolia<\/i>\n                    : A Comprehensive Review from Ethanobotanical Insights to Future Pharmacological Frontiers"],"prefix":"10.1002","volume":"21","author":[{"given":"Sara","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Pharmacy Integral University  Kursi Road, Dasauli Lucknow, Uttar Pradesh 226026 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9613-2873","authenticated-orcid":false,"given":"Farogh","family":"Ahsan","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Integral University  Kursi Road, Dasauli Lucknow, Uttar Pradesh 226026 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarique","family":"Mahmood","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Integral University  Kursi Road, Dasauli Lucknow, Uttar Pradesh 226026 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahzadi","family":"Bano","sequence":"additional","affiliation":[{"name":"Department of Chemistry Integral University  Kursi Road, Dasauli Lucknow, Uttar Pradesh 226026 India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,28]]},"reference":[{"key":"e_1_2_13_1_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43094-019-0015-8"},{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40816-021-00271-7"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1207-9469"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21050559"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecam\/nem096"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.07.074"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-121464"},{"key":"e_1_2_13_8_1","first-page":"116","volume-title":"Phytochemicals as Lead Compounds for New Drug Discovery","author":"Egbuna C.","year":"2020"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/c3np20120a"},{"key":"e_1_2_13_10_1","first-page":"67","volume-title":"Indian Trees : An Account of Trees, Shrubs, Woody Climbers, Bamboos, and Palms Indigenous or Commonly Cultivated in the British Indian Empire","author":"Brandis D.","year":"2007"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3841.2009.01244.x"},{"key":"e_1_2_13_12_1","unstructured":"C. Orwa A. Mutua R. Kindt R. Jamnadass A. Simons Agroforestry Database: A Tree Reference and Selection Guide 2009 4 1\u20135."},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2010.12.011"},{"key":"e_1_2_13_14_1","first-page":"19","volume-title":"Med. Combretaceae India","author":"Ray P.","year":"2024"},{"key":"e_1_2_13_15_1","first-page":"120","volume":"6","author":"Fred Crossia James Rex Prabhu W.","year":"2019","journal-title":"J. Emerg. Technol. Innov. Res."},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40816-019-0148-5"},{"key":"e_1_2_13_17_1","first-page":"41","volume":"2","author":"Patil U.","year":"2011","journal-title":"Int. J. Pharma Sci. Res."},{"key":"e_1_2_13_18_1","first-page":"2224","volume":"2","author":"Dachani S.","year":"2012","journal-title":"J. Nat. Sci. Res."},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.22159\/ijpps.2022v14i11.45593"},{"key":"e_1_2_13_20_1","unstructured":"B.\u2005K. Prashanth \u201chttps:\/\/www.easyayurveda.com\/2016\/07\/21\/dhava-anogeissus-latifolia-axle-wood-tree\/ \u201d2023."},{"key":"e_1_2_13_21_1","unstructured":"CABI Anogeissus Latifolia (Axle-Wood Tree) 2019."},{"key":"e_1_2_13_22_1","first-page":"181","volume":"36","author":"Sankhyan H.","year":"2013","journal-title":"Indian J. For."},{"key":"e_1_2_13_23_1","first-page":"47","volume":"78","author":"Kumar M.","year":"2008","journal-title":"Tanzania J. For. Nat. Conserv."},{"key":"e_1_2_13_24_1","first-page":"2320","volume":"9","author":"Chandraiah G.","year":"2021","journal-title":"Int. J. Creat. Res. Thoughts"},{"key":"e_1_2_13_25_1","first-page":"77","volume":"1","author":"Mann A.","year":"2009","journal-title":"Med. Plants - Int. J. Phytomedicines Relat. Ind."},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43621-022-00076-9"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11270-020-04803-8"},{"key":"e_1_2_13_28_1","first-page":"e623","volume":"9","author":"Urolagin D.","year":"2024","journal-title":"Int. J. Nov. Res. Dev."},{"key":"e_1_2_13_29_1","first-page":"287","volume":"4","author":"Dubey R.","year":"2012","journal-title":"J. Pharmacogn. Phytochem."},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-4514.2005.00031.x"},{"key":"e_1_2_13_31_1","first-page":"641","volume":"14","author":"Deshpande V.","year":"1976","journal-title":"Indian J. Chem. Sect. B"},{"key":"e_1_2_13_32_1","first-page":"544","volume":"43","author":"Reddy K.","year":"1974","journal-title":"Curr. Sci."},{"key":"e_1_2_13_33_1","first-page":"129","volume":"3","author":"Reddy K.","year":"1965","journal-title":"Indian J. Chem."},{"key":"e_1_2_13_34_1","first-page":"83","volume":"6","author":"Sodipo O.","year":"2000","journal-title":"Global J. Pure Appl. Sci."},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1017\/jns.2016.41"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/np9904509"},{"key":"e_1_2_13_37_1","first-page":"33","volume":"2","author":"Ananth P. H.","year":"2012","journal-title":"Int. J. Pharm."},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.21760\/jaims.8.6.28"},{"key":"e_1_2_13_39_1","first-page":"39","volume-title":"Terpenoids","author":"Ludwiczuk A.","year":"2017"},{"key":"e_1_2_13_40_1","first-page":"691","volume-title":"Nat. Prod. Woody Plants. Springer Ser. Wood Sci.","author":"Dev S.","year":"1989"},{"key":"e_1_2_13_41_1","first-page":"102","volume":"15","author":"Yang W.","year":"2020","journal-title":"Nat. Prod. Commun."},{"key":"e_1_2_13_42_1","first-page":"446","volume":"2","author":"Singh A.","year":"2010","journal-title":"Pharmacologyonline"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.3109\/07388558809146602"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-01125-5"},{"key":"e_1_2_13_45_1","first-page":"393","volume":"67","author":"Hassan N. F.","year":"2024","journal-title":"Egypt. J. Chem."},{"key":"e_1_2_13_46_1","first-page":"106","volume":"3","author":"Hassan N. F.","year":"2023","journal-title":"Azhar Int. J. Pharm. Med. Sci."},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2016.08.025"},{"key":"e_1_2_13_48_1","first-page":"937","volume":"1","author":"Shanny D.","year":"2011","journal-title":"Pharmacologyonline"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.27.1266"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-8258.150925"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2222-1808(12)60229-1"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.3329\/dujps.v7i1.1217"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2005.12.002"},{"key":"e_1_2_13_54_1","first-page":"238","volume":"31","author":"Chaturvedi S.","year":"1987","journal-title":"Indian Perfum."},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0975-3575(10)80014-8"},{"key":"e_1_2_13_56_1","first-page":"265","volume":"7","author":"Phull P.","year":"1995","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"e_1_2_13_57_1","first-page":"677","volume":"2","author":"Rajender A.","year":"2011","journal-title":"Int. J. Res. Ayurveda Pharm."},{"key":"e_1_2_13_58_1","first-page":"2504","volume":"3","author":"Rajani A.","year":"2014","journal-title":"World J. Pharm. Res."},{"key":"e_1_2_13_59_1","first-page":"68","volume":"11","author":"Bisht P.","year":"2019","journal-title":"Int. J. Pharm. Res."},{"key":"e_1_2_13_60_1","first-page":"1974","volume":"7","author":"Parvathi K. M.","year":"2009","journal-title":"Int. J. Chem. Sci."},{"key":"e_1_2_13_61_1","first-page":"1","volume":"23","author":"Mahadevappa P.","year":"2009","journal-title":"Asian J. Exp. Sci."},{"key":"e_1_2_13_62_1","first-page":"1024","volume":"2","author":"Shekshavali T.","year":"2010","journal-title":"Pharmacologyonline"},{"key":"e_1_2_13_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2005.03.002"},{"key":"e_1_2_13_64_1","first-page":"649","volume":"8","author":"Parvathi K.","year":"2013","journal-title":"Bioscan"},{"key":"e_1_2_13_65_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.4816"},{"key":"e_1_2_13_66_1","doi-asserted-by":"publisher","DOI":"10.22159\/ajpcr.2018.v11i11.27651"},{"key":"e_1_2_13_67_1","first-page":"407","volume":"3","author":"Rajeshwar Y.","year":"2016","journal-title":"Int. J. Res. Appl."},{"key":"e_1_2_13_68_1","first-page":"303","volume":"2","author":"Khan S.","year":"2008","journal-title":"Pharmacologyonline"},{"key":"e_1_2_13_69_1","first-page":"12","volume":"5","author":"Parvathi K.","year":"2009","journal-title":"Pharmacogn. Mag."},{"key":"e_1_2_13_70_1","doi-asserted-by":"publisher","DOI":"10.1515\/jcim-2016-0130"},{"key":"e_1_2_13_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2007.07.024"},{"key":"e_1_2_13_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)41379-3"},{"key":"e_1_2_13_73_1","first-page":"331","volume":"54","author":"Govindarajan R.","year":"2004","journal-title":"Acta Pharm."},{"key":"e_1_2_13_74_1","first-page":"136","volume":"2","author":"Hemamalini K.","year":"2011","journal-title":"Int. J. Res. Pharm. Biomed. Sci."},{"key":"e_1_2_13_75_1","first-page":"219","volume-title":"Handbook of Experimental Pharmacology","author":"Kulkarni S.","year":"2012"},{"key":"e_1_2_13_76_1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0022-3565(25)05100-6","volume":"106","author":"Swinyard E. A.","year":"1952","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"e_1_2_13_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2007.12.021"},{"key":"e_1_2_13_78_1","first-page":"069","volume":"8","author":"Sharma V. C.","year":"2018","journal-title":"J. Appl. Pharmacol."},{"key":"e_1_2_13_79_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-015-0564-z"},{"key":"e_1_2_13_80_1","first-page":"221","volume-title":"Indian Medicinal Plants","author":"Kirtikar K. R.","year":"1975"},{"key":"e_1_2_13_81_1","first-page":"583","volume":"6","author":"Nag A.","year":"2007","journal-title":"Indian J. Tradit. Know."},{"key":"e_1_2_13_82_1","first-page":"174","volume-title":"Ethnobotany of Jalgaon District Maharashtra","author":"Pawar S.","year":"2008"},{"key":"e_1_2_13_83_1","first-page":"522","volume":"9","author":"Jain S. P.","year":"2010","journal-title":"Indian J. Tradit. Know."},{"key":"e_1_2_13_84_1","first-page":"91","volume":"9","author":"Bhakuni D. S.","year":"1971","journal-title":"Indian J. Exp. Biol."},{"key":"e_1_2_13_85_1","doi-asserted-by":"publisher","DOI":"10.3390\/polym14183836"},{"key":"e_1_2_13_86_1","doi-asserted-by":"publisher","DOI":"10.25004\/IJPSDR.2019.110619"},{"key":"e_1_2_13_87_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-10-52"},{"key":"e_1_2_13_88_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2015.16.15.6423"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202401378","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.202401378","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202401378","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T11:13:26Z","timestamp":1773227606000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202401378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,28]]},"references-count":88,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/cbdv.202401378"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202401378","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,28]]},"assertion":[{"value":"2024-06-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202401378"}}