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In addition, lipopolysaccharide (LPS) induced inflammation model of RAW264.7 cells was used to evaluate the in\u2005vitro anti\u2010inflammatory activity of VPP\u2010I. The results showed that the relative molecular weight of VPP\u2010I was 2.355 KDa, which was mainly composed of mannose (Man), glucose (Glc) and galactose (Gal) in a ratio of 1\u2009:\u200932.46\u2009:\u200928.76. Moreover, the VPP\u2010I contained sugar alcohol derivatives of T\u2010DGlcp(1\u2192, \u21924)\u2010D\u2010Galp(1\u2192, \u21923,6)\u2010D\u2010Manp(1\u2192, \u21924)\u2010D\u2010Glcp(1\u2192, \u21926)\u2010D\u2010Galp(1\u2192 and \u21926)\u2010D\u2010Glcp(1\u2192. In vitro anti\u2010inflammatory results showed that VPP\u2010I could inhibit the secretion of IL\u2010\u03b2, IL\u20106 and TNF\u2010\u03b1 in RAW264.7 cells induced by LPS. Moreover, compared to the LPS group, the mRNA expression levels of iNOS, COX\u20102, IL\u2010\u03b2, IL\u20106 and TNF\u2010\u03b1 produced by RAW264.7 were significantly decreased after treatment with VPP\u2010I (P&lt;0.05). In addition, VPP\u2010I could increase the SOD and GSH\u2212Px enzymes activity and decrease the content of MDA in LPS\u2010induced RAW264.7 cells (P&lt;0.05). In summary, this paper laid theoretical foundation for the application of Veronica persica Poir. in the field of medicine.<\/jats:p>","DOI":"10.1002\/cbdv.202401566","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T07:56:05Z","timestamp":1726818965000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Structural Characterization and Anti\u2010Inflammatory Activities of a Purified Polysaccharide from <i>Veronica persica Poir<\/i>."],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8046-4013","authenticated-orcid":false,"given":"Qiaoying","family":"Song","sequence":"first","affiliation":[{"name":"College of Biotechnology and Food Science Anyang Institute of Technology  Huanghe Road Anyang 455000 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingbiao","family":"Gu","sequence":"additional","affiliation":[{"name":"College of Biotechnology and Food Science Anyang Institute of Technology  Huanghe Road Anyang 455000 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingqi","family":"Kong","sequence":"additional","affiliation":[{"name":"College of Biotechnology and Food Science Anyang Institute of Technology  Huanghe Road Anyang 455000 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,31]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.14715\/cmb\/2018.64.8.2"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115898"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113264"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2017.11.008"},{"key":"e_1_2_8_5_1","volume":"50","author":"Liu H.","year":"2024","journal-title":"Int. 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