{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:07:42Z","timestamp":1753862862627,"version":"3.41.2"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T00:00:00Z","timestamp":1727913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82274205","82204763"],"award-info":[{"award-number":["82274205","82204763"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Four new norlignans, noralashinols D\u2212F (<jats:bold>1a\/b<\/jats:bold>\u2013<jats:bold>3<\/jats:bold>), and two known analogues (<jats:bold>4<\/jats:bold> and <jats:bold>5<\/jats:bold>) were isolated from the peeled stems of <jats:italic>Syringa pinnatifolia<\/jats:italic> Hemsl. The structures were elucidated by analysis of spectroscopic data, such as IR, HR\u2010ESI\u2010MS, 1D and 2D NMR, and ECD. All compounds were evaluated for anti\u2010inflammatory activities against NO production induced by LPS in BV<jats:sub>2<\/jats:sub> microglia cells. Compounds <jats:bold>1b<\/jats:bold> and <jats:bold>2<\/jats:bold> exhibited moderate activities with IC<jats:sub>50<\/jats:sub> values of 32.39\u00b19.1 and 47.83\u00b110.44\u2005\u03bcM, respectively, compared with positive control indomethacin (IC<jats:sub>50<\/jats:sub>=21.62\u2005\u03bcM). It is worth to note that <jats:bold>1<\/jats:bold>, <jats:bold>3<\/jats:bold>, and <jats:bold>4<\/jats:bold> have a distinctive woody fragrance.<\/jats:p>","DOI":"10.1002\/cbdv.202401567","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T02:58:56Z","timestamp":1723172336000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Noralashinols D\u2212F, New Norlignans from <i>Syringa pinnatifolia<\/i> and its Anti\u2010Inflammation in BV<sub>2<\/sub> Cells"],"prefix":"10.1002","volume":"21","author":[{"given":"Yana","family":"Liang","sequence":"first","affiliation":[{"name":"Modern Research Center for Traditional Chinese Medicine School of Chinese Materia Medica Beijing University of Chinese Medicine  Beijing 102448 P. R. 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