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The use of nanoparticles (NPs) in medicine is particularly quite revolutionary as it has opened new therapeutic avenues to diagnose, treat and manage diseases in an efficient and timely manner. The review article presents the biomedical applications of nanomaterials including bioimaging, magnetic hypothermia and photoablation therapy, with a particular focus on disease diagnosis and targeted drug delivery. Nanobiosensors are highly specific and can be delivered into cells to investigate important biomarkers. They are also used for targeted drug delivery and deliver theranostic agents to specific sites of interest. Other than these factors, the review also explores the role of nano\u2010based drug delivery systems for the management and treatment of nervous system disorders, tuberculosis and orthopaedics. The nano\u2010capsulated drugs can be transported by blood to the targeted site for a sustained release over a prolonged period. Some other applications like their role in invasive surgery, photodynamic therapy and quantum dot imaging have also been explored. Despite that, the safety concerns related to nanomedicine are also pertinent to comprehend as well as the biodistribution of NPs in the body and the mechanistic insight.<\/jats:p>","DOI":"10.1002\/cbdv.202401581","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T00:14:03Z","timestamp":1727136843000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Role of Nanomaterials in Diagnosis and Targeted Drug Delivery"],"prefix":"10.1002","volume":"22","author":[{"given":"Ekhlakh","family":"Veg","sequence":"first","affiliation":[{"name":"Department of Chemistry Integral University  Lucknow 226026, U.P. India"},{"name":"Department of Chemistry Isabella Thoburn College  Lucknow 226007, U.P. 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