{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:10:16Z","timestamp":1773281416737,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T00:00:00Z","timestamp":1729900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T00:00:00Z","timestamp":1729900800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373786"],"award-info":[{"award-number":["82373786"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Polar fungi play a vital role as prolific sources of unique chemical structures and diverse bioactive compounds.\n                    <jats:italic>Eutypella<\/jats:italic>\n                    sp. D\u20101 is a fungus isolated from the Arctic, and six compounds were extracted from the fermentation broth. Their structures are elucidated from HRESIMS, NMR spectroscopy, and ECD calculations. Compounds\n                    <jats:bold>1\u20135<\/jats:bold>\n                    are newly discovered compounds, with compound\n                    <jats:bold>1<\/jats:bold>\n                    possessing a rare peroxide\u2010bridge structure. Compounds\n                    <jats:bold>1<\/jats:bold>\n                    \u2013\n                    <jats:bold>4<\/jats:bold>\n                    are categorized as pimarane\u2010type diterpenes, while compounds\n                    <jats:bold>5<\/jats:bold>\n                    and\n                    <jats:bold>6<\/jats:bold>\n                    belong to the eudesmanolide sesquiterpenes. Compound\n                    <jats:bold>4<\/jats:bold>\n                    demonstrates anti\u2010inflammatory activity by inhibiting lipopolysaccharide\u2010induced nitric oxide release in RAW264.7 cells. Compounds\n                    <jats:bold>4<\/jats:bold>\n                    and\n                    <jats:bold>5<\/jats:bold>\n                    show antibacterial activity against\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202401750","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T06:15:32Z","timestamp":1724998532000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Discovery of Bioactive Terpenes Derived from a Polar Fungus"],"prefix":"10.1002","volume":"21","author":[{"given":"Yaodong","family":"Ning","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biology College of Basic Medical Sciences Naval Medical University  Shanghai 200433 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingxin","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology College of Basic Medical Sciences Naval Medical University  Shanghai 200433 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeqin","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology College of Basic Medical Sciences Naval Medical University  Shanghai 200433 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology College of Basic Medical Sciences Naval Medical University  Shanghai 200433 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology College of Basic Medical Sciences Naval Medical University  Shanghai 200433 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binghua","family":"Jiao","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology College of Basic Medical Sciences Naval Medical University  Shanghai 200433 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1151-562X","authenticated-orcid":false,"given":"Xiaoling","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology College of Basic Medical Sciences Naval Medical University  Shanghai 200433 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,26]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.3390\/md15030028"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/md18080401"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112957"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2013.104"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2017.1286486"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b00700"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26020315"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/md21100541"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2024.1349151"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.201700501"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/md14030044"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2017.1285301"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202401750","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.202401750","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202401750","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T11:17:10Z","timestamp":1773227830000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202401750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,26]]},"references-count":12,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/cbdv.202401750"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202401750","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,26]]},"assertion":[{"value":"2024-07-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202401750"}}