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The study investigates the wound\u2010healing properties of methanolic extracts from the plant's stems, leaves, and roots. GC\u2010MS disclosed cadaverine, dihydroxy\u20103,3\u2010dimethyl\u20103\u2010hydroxy\u2010<jats:italic>N<\/jats:italic>\u2010isopropylbutyramide, phthalic acid\u2010di(2\u2010propylpentyl)ester, and benzo[h]quinolone\u20102,4\u2010dimethyl in stem along with betamethasone valerate, 17\u2010pentatriacontene, 1,1\u2010cyclobutanedicarboxmide, heptadecane\u20109\u2010hexyl, cyclohexanol\u20102\u2010methylene\u20103(1\u2010methylethenyl) and pentacyclo[12.3.0.0(1,13).0(2,10).0(5,9)]hepatodecane\u20106\u2010ol\u201015\u2010one in leaf extracts and 2\u2010myristynonyl pantetheine, 7,8\u2010epoxylanostan\u201011\u2010ol\u20103\u2010acetoxy, heneicosane (1\u2010(1\u2010ethyl propyl)), 2\u2010piperidinone\u2010<jats:italic>N<\/jats:italic>\u2010[4\u2010bromobutyl] and 1\u2010monolinoleoylglycerol trimethyl silyl ether in the root extract. The antioxidant activity was assessed using several assays including DPPH, bound iron %, ABTS, total flavonoid content, and total phenolic content. The methanolic stem extract (MSE) showed the highest antioxidant capacity compared to the leaf and root extracts. The stem extract demonstrated the highest wound\u2010healing potential, followed by leaves and roots in albino mice. The findings were supported by computational analysis, which revealed that the binding interactions of phytochemicals from stem have more affinity than leaf and root with specific receptor sites. The <jats:italic>in\u2010silico<\/jats:italic> analysis ascertains that dihydroxy\u20103,3\u2010dimethyl\u20103\u2010hydroxy\u2010<jats:italic>N<\/jats:italic>\u2010isopropylbutyramide from MSE is the most effective wound\u2010healing agent. Moreover, ADME predictions demonstrated the drug\u2010like properties of the hit compounds.<\/jats:p>","DOI":"10.1002\/cbdv.202401821","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T02:20:04Z","timestamp":1728267604000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["GC\u2010MS Profiling, Pharmacological Predictions, Molecular Docking, and ADME Studies of Different Parts of <i>Thymus Linearis<\/i> against Multiple Target Proteins in Wound Healing"],"prefix":"10.1002","volume":"22","author":[{"given":"Sumaira","family":"Saleem","sequence":"first","affiliation":[{"name":"Department of Chemistry Government College University Lahore  54000 Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aamir","family":"Mushtaq","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences Government College University Lahore  54000 Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gulzar","family":"Muhammad","sequence":"additional","affiliation":[{"name":"Department of Chemistry Government College University Lahore  54000 Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Wajid","sequence":"additional","affiliation":[{"name":"Gulab Devi Institute of Pharmacy GDEC  Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4358-5259","authenticated-orcid":false,"given":"Farhan","family":"Siddique","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry Faculty of Pharmacy Bahauddin Zakariya University  Multan 60800 Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahad M.","family":"Alshabrmi","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratories College of Applied Medical Sciences Qassim University  Buraydah 51452 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faris F.","family":"Aba Alkhayl","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratories College of Applied Medical Sciences Qassim University  Buraydah 51452 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eid A.","family":"Alatawi","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Technology Faculty of Applied Medical Sciences University of Tabuk  Tabuk 71491 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"e_1_2_11_1_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.20.2192"},{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.9734\/BJPR\/2011\/403"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0043-31442006000400002"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000357477"},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","unstructured":"F.\u2005G. 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