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The SEM images and DLS analyses revealed HT\u2010based MOFs are &lt;micrometer sizes with the highest surface area value of 49.2\u2005m<jats:sup>2<\/jats:sup>\/g for HT\u2212Fe(III) MOFs. Interestingly, HT\u2010based MOFs exhibit fluorescent properties at \u03bb<jats:sub>em<\/jats:sub>=330\u2005nm with fluorescence intensities of 11485, 2120, and 6790 (a.u) for HT\u2212Cu(II), Fe(II), and Fe(III) MOFs, respectively. Moreover, HT\u2010based MOFs inhibited \u03b1\u2010glucosidase enyzme in a concentration\u2010dependent manner e.\u2009g., 33.1\u2009%, 69.8\u2009%, and 59.7\u2009% of C<jats:sub>enzyme<\/jats:sub>=500\u2005mg\/mL was inhibited by HT\u2212Cu(II)\u2010MOF, HT\u2212Fe(II)\u2010MOF, and HT\u2212Fe(III)\u2010MOFs, respectively. The minimum bactericidal concentration (MBC) values of HT\u2212Cu(II) MOFs for <jats:italic>Escherichia coli<\/jats:italic> (gram \u2212), <jats:italic>Staphylococcus aureus<\/jats:italic> (gram +), and <jats:italic>Candida albicans<\/jats:italic> are determined as 5, 5, and 10\u2005mg\/mL, respectively. Also, the antioxidant activities of 250\u2005ppm HT\u2010based MOF based on total phenol content (TPC) tests revealed 279, 208, 124, and 152\u2005mg.gallic acid equivalent\/mL (mg GA equivalency\/mL) for HT, HT\u2212Cu(II) MOF, HT\u2212Fe(II) MOF, and HT\u2212Fe(III), respectively affirming that antioxidant properties were retained. 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