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This study examines the potential antioxidant properties and \u03b1\u2010amylase inhibitory activity of <jats:italic>Artemisia campestris<\/jats:italic> leaves extract (<jats:italic>Artemisia campestris<\/jats:italic> L) and its effects on rats with induced PCOS. Estradiol valerate was administered to ten mature Wistar rats to induce PCOS, while a control group consisted of five mature Wistar rats. Following a 16\u2010day induction period, the rats were categorized into three groups: a control group, a PCOS group, and an experimental group receiving 200\u2005mg\/kg body weight of <jats:italic>A. campestris<\/jats:italic> L. extract orally for 15\u2005days. Serum levels of follicle\u2010stimulating hormone (FSH) and luteinizing hormone (LH) were measured using the ELISA technique. The group treated with <jats:italic>A. campestris<\/jats:italic> L. extract exhibited significantly reduced LH levels compared to the PCOS group. Histomorphometric analysis indicated notable changes in follicle counts and the thickness of the theca layer. These findings suggest a significant alleviation of PCOS symptoms, potentially linked to the effects of <jats:italic>A. campestris<\/jats:italic> L. on oxidative stress pathways. Furthermore, aqueous extracts of <jats:italic>A. campestris<\/jats:italic> L. displayed potent in\u2005vitro inhibition of \u03b1\u2010amylase, with an IC50 value of 2.418\u2005\u03bcg\/mL.<\/jats:p>","DOI":"10.1002\/cbdv.202402184","type":"journal-article","created":{"date-parts":[[2024,10,27]],"date-time":"2024-10-27T09:29:06Z","timestamp":1730021346000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Assessment of <i>Artemisia Campestris<\/i> L. 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