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This study synthesized silver NPs (Ag NPs), zinc oxide NPs (ZnO NPs), and silver\u2010doped zinc oxide NPs (Ag\/ZnO NPs) using termite wing biowaste (<jats:italic>Odontotermes obesus<\/jats:italic>). The synthesized NPs were characterized by UV\u2013visible spectroscopy, FTIR, SEM\u2010EDX, XRD, and atomic force microscopy (AFM), confirming successful biosynthesis and purity. AFM provided 3D profiling of the average sizes of 28.4, 19.6, and 11\u00a0nm for Ag NPs, ZnO NPs, and Ag\/ZnO NPs, respectively. Among these three NPs, Ag\/ZnO NPs showed superior antioxidant activity in DPPH (86\u00a0\u00b1\u00a03.61%), ABTS (76\u00a0\u00b1\u00a01.5%), and nitric oxide assays (77\u00a0\u00b1\u00a01%). In vitro studies demonstrated their significant antibacterial and anticancer potential against <jats:italic>Escherichia coli<\/jats:italic>, <jats:italic>Staphylococcus aureus<\/jats:italic>, and HeLa cells, with &gt;80% cell viability reduction at 100\u00a0\u00b5g\/mL. These findings highlight the potential of Ag\/ZnO NPs as antioxidants, antibacterial agents, and anticancer agents, warranting further in vivo studies for biomedical applications.<\/jats:p>","DOI":"10.1002\/cbdv.202402466","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T09:59:25Z","timestamp":1741687165000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Biosynthesis and Characterization of Termites Wings Extract Derived Silver, Zinc, and Silver\u2010Doped Zinc Oxide Nanoparticles for Antioxidant and Anticancer Activity"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0576-7318","authenticated-orcid":false,"given":"Parthasarathy","family":"Surya","sequence":"first","affiliation":[{"name":"Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail T.","family":"Bello","sequence":"additional","affiliation":[{"name":"Department of Physics, College of Science, Engineering and Technology University of South Africa Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. S.","family":"Sathishkumar","sequence":"additional","affiliation":[{"name":"National Centre for Coastal Research (NCCR), Ministry of Earth Sciences (MoES), NIOT Campus, Pallikaranai Chennai Tamil Nadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahani Awad","family":"Alahmadi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Medicine and King Khalid University Hospital Medical City King Saud University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hesham S.","family":"Almoallim","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery College of Dentistry, King Saud University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajadesingu Suriya","family":"Prakash","sequence":"additional","affiliation":[{"name":"Centre for Research in Environment, Sustainability Advocacy and Climate Change (REACH) SRM Institute of 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