{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:50:42Z","timestamp":1787727042552,"version":"build-2784847793"},"reference-count":122,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    causes nosocomial infections and chronic diseases.\n                    <jats:italic>Cinnamomum cassia<\/jats:italic>\n                    and\n                    <jats:italic>Syzygium aromaticum<\/jats:italic>\n                    are used natural antimicrobials. Essential oil (EO) from\n                    <jats:italic>C. cassia<\/jats:italic>\n                    (CCEO) and\n                    <jats:italic>S. aromaticum<\/jats:italic>\n                    (CEO) was characterized using GC\u2010MS analysis. Eugenol (82.31%), eugenol acetate (10.57%), and \u03b2\u2010caryophyllene (3.41%) were major constituents in CEO while cinnamaldehyde (88.18%), cinnamyl acetate (2.85%) and 2\u2010methoxy cinnamaldehyde (1.77%) were main components in CCEO. The EOs and major constituents exhibited good antimicrobial activity against clinical strains of\n                    <jats:italic>P. aeruginosa<\/jats:italic>\n                    . Cinnamaldehyde exhibited the best antimicrobial effect with minimal inhibitory concentration (MIC) as low as 0.031% \u00b1 0.07% (v\/v) and inhibition zones reaching 30 \u00b1 0.5\u00a0mm diameter. Test samples showed antibiofilm activities against two culture types and seven clinical strains of\n                    <jats:italic>P. aeruginosa<\/jats:italic>\n                    at concentrations of 2MIC to MIC\/4. CCEO and its major constituent cinnamaldehyde were more active, compared to CEO and its major constituent eugenol. Scanning electron microscopy images showed untreated colonies with well\u2010developed biofilms while there was significant reduction of biofilms with distorted architecture and cell shrinkage upon treatment with test samples. In silico studies indicated great interactions between the major compounds, eugenol and cinnamaldehyde, with the receptor proteins of\n                    <jats:italic>P. aeruginosa<\/jats:italic>\n                    revealed by negative binding energies. Eugenol and cinnamaldehyde exhibited appreciable druglikeness.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202402693","type":"journal-article","created":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T07:00:17Z","timestamp":1735542017000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Inhibition of Clinical Multidrug\u2010Resistant\n                    <i>Pseudomonas aeruginosa<\/i>\n                    Biofilms by Cinnamaldehyde and Eugenol From Essential Oils: In Vitro and In Silico Analysis"],"prefix":"10.1002","volume":"22","author":[{"given":"Asma","family":"Benaissa","sequence":"first","affiliation":[{"name":"Laboratory of Applied Microbiology in Food, Biomedical, and Environment (LAMAABE), Department of Biology, Faculty of Sciences of Nature, Life, Earth, and Universe Abou Bekr Belka\u00efd University of Tlemcen  Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wafaa","family":"Bouali","sequence":"additional","affiliation":[{"name":"Laboratory Antifungal, Antibiotic, Physico\u2010chemical, Synthesis and Biological Activity, Department of Biology, Faculty of Natural Sciences and Life, Sciences of the Earth and the Universe University Abou Bekr Belkaid Tlemcen  Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6683-3337","authenticated-orcid":false,"given":"Alfred","family":"Ngenge Tamfu","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering, School of Chemical Engineering and Mineral Industries University of Ngaoundere  Ngaoundere Cameroon"},{"name":"Food Quality Control and Analysis Program, Ula Ali Kocman Vocational School Mugla Sitki Kocman University  Mugla Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bousselham","family":"Ammara","sequence":"additional","affiliation":[{"name":"Microbiology Laboratory University Hospital Center of Tlemcen  Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selcuk","family":"Kucukaydin","sequence":"additional","affiliation":[{"name":"Department of Medical Services and Techniques, Koycegiz Vocational School of Health Services Mugla Sitki Kocman University  Mugla Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nawel","family":"Latti","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Microbiology in Food, Biomedical, and Environment (LAMAABE), Department of Biology, Faculty of Sciences of Nature, Life, Earth, and Universe Abou Bekr Belka\u00efd University of Tlemcen  Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelmounaim","family":"Khadir","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Microbiology in Food, Biomedical, and Environment (LAMAABE), Department of Biology, Faculty of Sciences of Nature, Life, Earth, and Universe Abou Bekr Belka\u00efd University of Tlemcen  Tlemcen Algeria"},{"name":"Department of Biology Oran University  Oran Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mourad","family":"Bendahou","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Microbiology in Food, Biomedical, and Environment (LAMAABE), Department of Biology, Faculty of Sciences of Nature, Life, Earth, and Universe Abou Bekr Belka\u00efd University of Tlemcen  Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El Hassane","family":"Anouar","sequence":"additional","affiliation":[{"name":"Department of Chemistry, College of Sciences and Humanities in Al\u2010Kharj Prince Sattam bin Abdulaziz University  Al\u2010Kharj Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozgur","family":"Ceylan","sequence":"additional","affiliation":[{"name":"Food Quality Control and Analysis Program, Ula Ali Kocman Vocational School Mugla Sitki Kocman University  Mugla Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/app.53631"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13205-020-02509-6"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/bab.2545"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27154872"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2014.05.002"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens9010006"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.procbio.2020.06.001"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.15406\/jmen.2014.01.00014"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20143423"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2017.09.016"},{"issue":"9","key":"e_1_2_11_12_1","first-page":"1299","article-title":"Biofilms: A Survival Strategy of Bacteria","volume":"85","author":"Prakash B.","year":"2003","journal-title":"Current Science"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/9781555817466.ch14"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2020.104191"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmic.2023.100084"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002480-200011000-00037"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rechem.2022.100322"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/apm.12688"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2014.11.017"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wjorl.2016.03.002"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-009-0940-9"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.2007.03287.x"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-020-00397-y"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0954411914556137"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/lam.13127"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)05321-1"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-015-2323-z"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43141-021-00242-y"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky042"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-019-0533-3"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6941.12344"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1590\/0001-3765202120201507"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imj.2023.05.003"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.926758"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2016.1177460"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00430-012-0277-7"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.001199"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00138-18"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21228671"},{"key":"e_1_2_11_40_1","first-page":"227","volume-title":"Pseudomonas aeruginosa Quorum Sensing and Biofilm Inhibition,\u201d in Quorum Sensing","author":"G\u00f6kals\u0131n B.","year":"2019"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1177\/17475198231184603"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.3897\/pharmacia.69.e87834"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-023-04115-4"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2023.154973"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12010-023-04380-6"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods11030464"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2022.e12472"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1177\/1934578X211044565"},{"key":"e_1_2_11_49_1","doi-asserted-by":"crossref","DOI":"10.1177\/1934578X211024039","article-title":"Anti\u2010quorum Sensing and Antioxidant Activity of Essential Oils Extracted From Juniperus Species, Growing Spontaneously in Tebessa Region (East of Algeria)","volume":"16","author":"Boudiba S.","year":"2021","journal-title":"Natural Products Communications"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7405736"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2017.10.054"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules180910930"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24193473"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants12020358"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.17660\/th2020\/75.5.5"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1021\/np50085a029"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1577\/1548-8675(1997)017<0301:TUOCOA>2.3.CO;2"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.010538-0"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-15-593"},{"issue":"6","key":"e_1_2_11_60_1","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/ptr.2124","article-title":"The Chemical Composition and Biological Activity of Clove Essential Oil, Eugenia caryophyllata (Syzigium aromaticum L. Myrtaceae): A Short Review","volume":"21","author":"Chaieb K.","year":"2007","journal-title":"Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26237407"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10020202"},{"issue":"2","key":"e_1_2_11_63_1","first-page":"86","article-title":"Antibacterial and Antifungal Activity of Clove Extract (Syzygium aromaticum)","volume":"2","author":"Hiwandika N.","year":"2021","journal-title":"Eureka Herba Indonesia"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.01.045"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants10102185"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1080\/1040841X.2017.1295225"},{"key":"e_1_2_11_67_1","first-page":"251","volume-title":"Determination of Essential Oils in Herbal Drugs","author":"European Pharmacopoeia","year":"2008"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1177\/1934578X211044565"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/17.19.7843"},{"key":"e_1_2_11_70_1","unstructured":"European Committee on Antimicrobial Susceptibility Testing Comit\u00e9 de L'antibiogramme de la Soci\u00e9t\u00e9 Fran\u00e7aise De Microbiologie (CA\u2010SFM). Recommandations 2020. (Paris:Soci\u00e9t\u00e9 Fran\u00e7aise De Microbiologie 2020)."},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11164-013-1267-0"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.20307\/nps.2023.29.4.225"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.521"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1177\/1934578X241245234"},{"issue":"47","key":"e_1_2_11_75_1","article-title":"Microtiter Dish Biofilm Formation Assay","author":"O'Toole G. A.","year":"2011","journal-title":"JoVE (Journal of Visualized Experiments)"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.5897\/AJMR2016.8203"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2007.01.006"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb-2019-0204"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28124802"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29112456"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46401\u20100"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2019.04.001"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2018.11.013"},{"key":"e_1_2_11_84_1","first-page":"78","article-title":"Pathogenic Factors of Pseudomonas aeruginosa\u2014The Role of Biofilm in Pathogenicity and as a Target for Phage Therapy","volume":"71","author":"Al\u2010Wrafy F.","year":"2017","journal-title":"Advances in Hygiene and Experimental Medicine"},{"key":"e_1_2_11_85_1","first-page":"183","article-title":"Antimicrobial Effects of Indonesian Medicinal Plants Extracts on Planktonic and Biofilm Growth of Pseudomonas aeruginosa and Staphylococcus aureus","volume":"7","author":"Pratiwi S. U.","year":"2015","journal-title":"International Journal of Pharmacy and Pharmaceutical Sciences"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2015-9442"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2022.2499-2505"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2184.2006.00384.x"},{"issue":"4","key":"e_1_2_11_89_1","first-page":"257","article-title":"Comparison Studies on Chemical Constituents of Essential Oil From Ramulus Cinnamomi and Cortex Cinnamomi by GC\u2010MS","volume":"25","author":"Shen Q.","year":"2002","journal-title":"Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ifset.2008.12.002"},{"issue":"3","key":"e_1_2_11_91_1","first-page":"4","article-title":"Investigation on Cinnamon Resource, Growth and Yield of Oil in Guangxi and Yunnan","volume":"27","author":"Xu Y.","year":"2004","journal-title":"Tropical Agricultural Science & Technology"},{"issue":"3","key":"e_1_2_11_92_1","first-page":"288","article-title":"Study on Chemical Components of Essential Oils in Cinnamomum cassia Presl From Different Growth Years by GC\u2010MS","volume":"25","author":"Huang J.\u2010W.","year":"2005","journal-title":"Chinese Journal of Pharmaceutical Analysis"},{"key":"e_1_2_11_93_1","first-page":"9","article-title":"Annual Variation Laws of Main Chemical Compositions and Oil Yielding Rate in Branches and Leaves of Cinnamomum cassia","volume":"24","author":"Qin Y.","year":"2006","journal-title":"Nonwood Forest Research"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-64.7.1019"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X06004041"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2022.106009"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1080\/08927014.2017.1350655"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1590\/1981-6723.14418"},{"issue":"2","key":"e_1_2_11_99_1","first-page":"137","article-title":"Bactericidal Effects of Essential Oils From Clove, Lavender and Geranium on Multi\u2010drug Resistant Isolates of Pseudomonas aeruginosa","volume":"4","author":"Mahboobi M.","year":"2006","journal-title":"Iranian Journal of Biotechnology"},{"key":"e_1_2_11_100_1","first-page":"1","article-title":"Antibacterial Activity of Essential Oils Extracts From Cinnamon, Thyme, Clove and Geranium Against a Gram Negative and Gram Positive Pathogenic Bacteria","volume":"3","author":"Oulkheir S.","year":"2017","journal-title":"Journal of Diseases and Medicinal Plants"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/759348"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1093\/jambio\/lxad305"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2019.104405"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00217-012-1694-y"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26185598"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.07499-11"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2014.11.028"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.70.12.6951-6956.2004"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000692"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.4103\/ayu.AYU_101_19"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12038-013-9385-9"},{"key":"e_1_2_11_112_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10529-012-1126-x"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1111\/jam.15171"},{"key":"e_1_2_11_114_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0135495"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2023.117561"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01144"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(00)00129-0"},{"key":"e_1_2_11_118_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep46277"},{"key":"e_1_2_11_119_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389200218666170316093301"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e32834c6efd"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.0c01581"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.1080\/17425255.2021.1865309"},{"key":"e_1_2_11_123_1","doi-asserted-by":"publisher","DOI":"10.5114\/bta.2021.103765"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202402693","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbdv.202402693","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202402693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:34:01Z","timestamp":1773009241000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202402693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,7]]},"references-count":122,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/cbdv.202402693"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202402693","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,7]]},"assertion":[{"value":"2024-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202402693"}}