{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T21:11:06Z","timestamp":1789506666042,"version":"build-2803163510"},"reference-count":62,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Research on natural antioxidants derived from plants has surged due to their potential health benefits. In the current study, the chemical composition, enzyme inhibitory activity, and antimicrobial effects of the\n                    <jats:italic>Elaeagnus angustifolia<\/jats:italic>\n                    L. plant, including leaves, flowers, and flower stalk (FS) extracts, were analyzed. A total of 28 compounds were identified across the different plant parts, with 24 in flowers (F), 9 in FSs, and 14 in leaves (L). The antimicrobial activity of the extracts was evaluated using the disk diffusion method against two Gram\u2010positive (\n                    <jats:italic>Staphylococcus aureus and Bacillus cereus<\/jats:italic>\n                    ) and two Gram\u2010negative bacteria (\n                    <jats:italic>Escherichia coli and Klebsiella pneumoniae<\/jats:italic>\n                    ). The minimum inhibitory concentration (MIC) was determined as 3.13\u201312.50\u00a0mg\/mL. The measured zone diameters were also in the range of 5\u20138\u00a0mm. The results indicated that the methanol extracts exhibited significant antimicrobial properties. Additionally, the extracts demonstrated strong inhibition of cholinesterases (acetylcholinesterase [AChE]: 11.14\u00a0\u00b1\u00a00.11\u201318.11\u00a0\u00b1\u00a00.12\u00a0\u00b5g\/mL; butyrylcholinesterase [BChE]: 32.54\u00a0\u00b1\u00a00.55\u201344.61\u00a0\u00b1\u00a00.17\u00a0\u00b5g\/mL) and moderate inhibition against \u03b1\u2010glycosidase and tyrosinase enzymes. Moreover, the molecular docking interaction of\n                    <jats:italic>trans<\/jats:italic>\n                    \u2010ferulic, shikimic, and vanillic acids, the most abundant phenolic compounds in the extracts, with AChE, BChE, \u03b1\u2010glycosidase, and tyrosinase, was assessed using AutoDock Vina software.\n                    <jats:italic>E. angustifolia<\/jats:italic>\n                    L. possesses a high phenolic content and exhibits significant antioxidant and enzyme inhibitory capabilities, which may contribute to its extensive utilization in food and traditional medicine.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202402802","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T05:21:42Z","timestamp":1735795302000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Chemical Composition, Antimicrobial, and Enzyme Inhibitory Properties of\n                    <i>Elaeagnus angustifolia<\/i>\n                    L."],"prefix":"10.1002","volume":"22","author":[{"given":"Melek","family":"Zor","sequence":"first","affiliation":[{"name":"Department of Gastronomy and Culinary Arts, School of Tourism and Hotel Management A\u011fr\u0131 \u0130brahim \u00c7e\u00e7en University  A\u011fr\u0131 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00fcya","family":"Sa\u011flamta\u015f","sequence":"additional","affiliation":[{"name":"Medical Services and Techniques Department A\u011fr\u0131 \u0130brahim \u00c7e\u00e7en University  A\u011fr\u0131 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3216-1098","authenticated-orcid":false,"given":"Abdullah","family":"Demirci","sequence":"additional","affiliation":[{"name":"Central Research and Application Laboratory A\u011fr\u0131 \u0130brahim \u00c7e\u00e7en University  A\u011fr\u0131 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