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The ligand was subsequently reacted with copper(II) acetate to produce the corresponding Cu(II) complex (\n                    <jats:bold>\n                      CuL\n                      <jats:sub>2<\/jats:sub>\n                    <\/jats:bold>\n                    ). Both the ligand and its complex underwent characterization using various techniques including nuclear magnetic resonance, ultraviolet\u2010visible, Fourier\u2010transform infrared, thermogravimetric analysis, elemental analysis, and mass spectroscopy. In addition, the solid\u2010state structure of the complex was determined through single crystal X\u2010ray diffraction analysis, confirming the successful isolation of the compounds. Subsequently, the nematicidal activities of the ligand and its complex were assessed through in vitro egg hatching inhibition and mortality rate assays, in comparison to the control, carbofuran (\n                    <jats:bold>Crf<\/jats:bold>\n                    ), at concentrations of 50 and 100 \u00b5M over a 24\u201372\u2010h period. The results indicated the ligand's superiority over the complex in both assays at lower concentrations. At a concentration of 50 \u00b5M, the ligand\n                    <jats:bold>HL<\/jats:bold>\n                    demonstrated 100% egg\u2010hatching inhibition at 24, 48, and 72 h, whereas the complex\n                    <jats:bold>\n                      CuL\n                      <jats:sub>2<\/jats:sub>\n                    <\/jats:bold>\n                    showed egg\u2010hatching inhibition rates of 93.86 \u00b1 0.22%, 98.76 \u00b1 0.14%, and 99.33 \u00b1 0.52% at the same time intervals. The control,\n                    <jats:bold>Crf<\/jats:bold>\n                    , exhibited inhibition rates of 56.33 \u00b1 0.33%, 69.94 \u00b1 0.6%, and 67.00 \u00b1 0.34% over the same time period. Similarly, at a concentration of 100 \u00b5M, both the ligand and complex demonstrated 100% egg\u2010hatching inhibition at 24, 48, and 72 h, while the control showed egg\u2010hatching rates of 88.16 \u00b1 0.84%, 89.9 \u00b1 0.55%, and 90.8 \u00b1 0.50%. Regarding the mortality rate, at 50 and 100 \u00b5M, the ligand\n                    <jats:bold>HL<\/jats:bold>\n                    exhibited a 100% mortality rate within 24 to 72 h, whereas the complex\n                    <jats:bold>\n                      CuL\n                      <jats:sub>2<\/jats:sub>\n                    <\/jats:bold>\n                    displayed mortality rates of 56.66 \u00b1 0.33%, 63.3 \u00b1 0.23%, and 86.66 \u00b1 0.13% at 24, 48, and 72 h, respectively, with a mortality rate of 100% at 100 \u00b5M within the same time intervals. The control,\n                    <jats:bold>Crf<\/jats:bold>\n                    , demonstrated mortality rates of 54%\u201367% at 50 \u00b5M and 62%\u201378% at 100 \u00b5M within 24\u201372 h. Additionally, the density\u2010functional theory study revealed the electronic properties of the compounds, reinforcing the experimental findings.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202403033","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T15:54:36Z","timestamp":1737647676000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Synthesis, Characterization, Anti\u2010Nematicidal, and Computational Study of Copper(II) Complex Derived From Fluoro\u2010substituted Schiff Base Ligand"],"prefix":"10.1002","volume":"22","author":[{"given":"Salisu Y.","family":"Lawan","sequence":"first","affiliation":[{"name":"Department of Pure and Applied Chemistry University of Maiduguri Maiduguri Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0662-623X","authenticated-orcid":false,"given":"Naomi P.","family":"Ndahi","sequence":"additional","affiliation":[{"name":"Department of Pure and Applied Chemistry University of Maiduguri Maiduguri Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim B.","family":"Galadima","sequence":"additional","affiliation":[{"name":"Department of Crop Protection Faculty of Agriculture University of Maiduguri Maiduguri Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1192-1916","authenticated-orcid":false,"given":"Olaide O.","family":"Wahab","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences University of Johannesburg Doornfontein Campus Johannesburg South\u00a0Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3419-9516","authenticated-orcid":false,"given":"Tunde L.","family":"Yusuf","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Natural Science and Agricultural Science, University of Pretoria Pretoria South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3003-3025","authenticated-orcid":false,"given":"Louis\u2010Charl C.","family":"Coetzee","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of South Africa Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2805-6300","authenticated-orcid":false,"given":"Mostafa S. 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