{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T03:40:48Z","timestamp":1769744448112,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>From the methanol extract of the <jats:italic>Poria cocos<\/jats:italic> peels, two novel tetracyclic triterpenoid (<jats:bold>1\u20132<\/jats:bold>) and six known triterpenenes (<jats:bold>3\u20138<\/jats:bold>) were isolated. The structures of the new compounds were determined to be (20<jats:italic>R<\/jats:italic>)\u201016\u03b1,24,31\u2010trihydroxy\u20103,4\u2010seco\u2010lanosta\u20104(28),7,9(11)\u2010triene\u20103,21\u2010dioic acid 3\u2010oate (<jats:bold>1<\/jats:bold>), (20<jats:italic>R<\/jats:italic>)\u20103\u03b2,23\u2010dihydroxy\u2010lanosta\u20107,9(11),24(25)\u2010triene\u201021\u2010oic acid (<jats:bold>2<\/jats:bold>). Their structures were elucidated by analyses of the HRESI\/MS, 1D and 2D NMR spectra. All isolated triterpeoids were evaluated for their \u03b1\u2010glucosidase inhibitory activities in vitro. Compounds <jats:bold>2<\/jats:bold> and <jats:bold>6<\/jats:bold> exhibited moderate \u03b1\u2010glucosidase inhibitory activity with the IC<jats:sub>50<\/jats:sub> values of 132.1\u00a0\u00b1\u00a03.4 and 271.0\u00a0\u00b1\u00a05.2 \u00b5M, respectively.<\/jats:p>","DOI":"10.1002\/cbdv.202403062","type":"journal-article","created":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T03:21:22Z","timestamp":1742786482000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lanostane\u2010Type Triterpenes From <i>Poria cocos<\/i> Peels and Their \u03b1\u2010Glucosidase Inhibitory Activity"],"prefix":"10.1002","author":[{"given":"Yu\u2010Yu","family":"Xu","sequence":"first","affiliation":[{"name":"College of Food Science &amp; Engineering Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Yue","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Engineering Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Engineering Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong\u2010Hua","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Engineering Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ze\u2010Jun","family":"Zhao","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Engineering Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Tian","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Engineering Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4394-6985","authenticated-orcid":false,"given":"Ming","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science &amp; Engineering Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"5","article-title":"A Narrative Review Unveiling Novel Molecular Targets in Advancing Antidiabetic Medications: An Emerging Perspective","volume":"18","author":"Venkatesan B.","year":"2024","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.diabres.2021.109119","article-title":"IDF Diabetes Atlas: Global, Regional and Country\u2010Level Diabetes Prevalence Estimates for 2021 and Projections for 2045","volume":"183","author":"Sun H.","year":"2022","journal-title":"Diabetes Research and Clinical Practice"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"3419","DOI":"10.1038\/s41598-024-54021-z","article-title":"Synthesis, Molecular Docking and DFT Analysis of Novel bis\u2010Schiff Base Derivatives With Thiobarbituric Acid for \u03b1\u2010Glucosidase Inhibition Assessment","volume":"14","author":"Gul S.","year":"2024","journal-title":"Scientific Reports"},{"key":"e_1_2_7_5_1","first-page":"3207","article-title":"Effect of Liraglutide Combined With Metformin or Acarbose on Glucose Control in Type 2 Diabetes Mellitus and Risk Factors of Gastrointestinal Adverse","volume":"14","author":"Ren G. 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