{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T04:46:39Z","timestamp":1788497199867,"version":"build-2803163510"},"reference-count":59,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T00:00:00Z","timestamp":1753228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T00:00:00Z","timestamp":1753228800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The growing interest in natural and holistic approaches has increased research on medicinal plants, including\n                    <jats:italic>Salvia<\/jats:italic>\n                    species, known for their distinctive aroma, bioactive compounds, and health benefits. This study evaluated the phytochemical composition, antioxidant activity, and antimicrobial potential of water and ethanol extracts from\n                    <jats:italic>S. sclarea, S. huberi, S. fruticosa<\/jats:italic>\n                    , and\n                    <jats:italic>S. aethiopis<\/jats:italic>\n                    . Chemometric methods, including Pearson correlation, principal component analysis, and hierarchical clustering, were used to analyze experimental correlations. High\u2010performance liquid chromatography\u2010photodiode array identified protocatechuic acid as the dominant phenolic compound.\n                    <jats:italic>S. huberi<\/jats:italic>\n                    ethanol extract exhibited the highest antioxidant activity (1,1\u2010diphenyl\u20102\u2010picrylhydrazyl 50% inhibitory concentration [IC\n                    <jats:sub>50<\/jats:sub>\n                    ]: 0.25\u00a0mg\/mL, Iron\u2010chelating IC\n                    <jats:sub>50<\/jats:sub>\n                    : 3.05\u00a0mg\/mL), while\n                    <jats:italic>S. sclarea<\/jats:italic>\n                    had the highest total phenolic content (812.30\u00a0mg GAE\/g). Antimicrobial activity was observed in all extracts. These findings highlight that\n                    <jats:italic>S. huberi<\/jats:italic>\n                    has strong antioxidant potential. Further studies should explore the mechanisms of action and potential medical applications of\n                    <jats:italic>Salvia<\/jats:italic>\n                    species.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202403218","type":"journal-article","created":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T18:14:37Z","timestamp":1753294477000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Analysis of phytochemical profiles of different extracts of Salvia (S. sclarea, S. huberi, S. fruticosa and S. aethiopis) by HPLC\u2010PDA, evaluation of their antioxidant capacity and antimicrobial activity"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9720-8662","authenticated-orcid":false,"given":"Mevl\u00fcde Nur","family":"Dilgen","sequence":"first","affiliation":[{"name":"Department of Traditional, Complementary and Integrative Medicine, Biotherapeutic Product Development Program Ankara Yildirim Beyazit University  Ankara T\u00fcrkiye"},{"name":"Department of Biology Gazi University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bet\u00fcl","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"Department of Biology Gazi University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nil\u00fcfer","family":"Vural","sequence":"additional","affiliation":[{"name":"Department of Traditional, Complementary and Integrative Medicine, Biotherapeutic Product Development Program Ankara Yildirim Beyazit University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Ko\u00e7","sequence":"additional","affiliation":[{"name":"Department of Traditional, Complementary and Integrative Medicine, Biotherapeutic Product Development Program Ankara Yildirim Beyazit University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/0118722083278561231212072408"},{"key":"e_1_2_8_3_1","volume-title":"Medicinal Plants: Microbial Interactions, Molecular Techniques and Therapeutic Trends","author":"Safdar N.","year":"2023"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.52711\/2231\u20105713.2025.00009"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox6030070"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.116697"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.69613\/x8pa5g41"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3787818"},{"key":"e_1_2_8_9_1","first-page":"151","article-title":"Salvia spp.: An Update on Antioxidant Activity and Pharmacological Uses","author":"Porres\u2010Mart\u00ednez 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