{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:57:55Z","timestamp":1755226675000,"version":"3.43.0"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>This study investigated the chemical composition and biological activity of essential oil (EO) extracted from the leaves of <jats:italic>Oudneya africana<\/jats:italic> from Ouargla, using gas chromatography\u2010flame ionization detector\/mass spectrometry. A total of 35 compounds were identified, representing 87.45% of the oil composition, with hexacosane (34.94%), 2\u2010pentadecanone\u20106,10,14\u2010trimethyl (4.86%), and hexadecanoic acid methyl ester (3.45%) as major components. The EO demonstrated significant antimicrobial resistance against Gram\u2010positive and Gram\u2010negative bacteria, notably inhibiting <jats:italic>Staphylococcus aureus<\/jats:italic> and <jats:italic>Escherichia coli<\/jats:italic> growth (inhibition zones: 30.5 \u00b1 1\u00a0mm (34.44%) and 28.5 \u00b1 1\u00a0mm (32.22%), respectively), while showing minimal effect on <jats:italic>Pseudomonas aeruginosa<\/jats:italic>, it's also exhibited strong antifungal activity against <jats:italic>Aspergillus niger<\/jats:italic> at minimum concentration of 25\u00a0mg\/mL. Additionally, the EO displayed dose\u2010dependent anti\u2010diabetic potential through alpha\u2010amylase inhibition, with a half\u2010maximal inhibitory concentration value of 341.12 \u00b1 1.14\u00a0\u00b5g\/mL. However, its sun protection factor (SPF) was relatively low 8.96 \u00b1 0.06. This is the first report on the \u03b1\u2010amylase, antifungal, and SPF properties of <jats:italic>O. africana<\/jats:italic> EO, highlighting its potential as a source of natural compounds for medical application.<\/jats:p>","DOI":"10.1002\/cbdv.202403227","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T16:56:28Z","timestamp":1744044988000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gas Chromatography\u2010Mass Spectrometry Characterization and Bioactivity Study of <i>Oudneya africana<\/i> Leaves Essential Oil: Antidiabetic, Antimicrobial, and Photoprotective Activities"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4254-3428","authenticated-orcid":false,"given":"Kerkabou","family":"Abdeldjalil","sequence":"first","affiliation":[{"name":"Unit\u00e9 de recherche: Valorisation des Ressources Naturelles, Mol\u00e9cules Bioactives et Analyses Physico\u2010Chimiques et Biologiques (VARENBIOMOL) Universit\u00e9 Constantine1 Constantine Algeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slougui","family":"Nabila","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de recherche: Valorisation des Ressources Naturelles, Mol\u00e9cules Bioactives et Analyses Physico\u2010Chimiques et Biologiques (VARENBIOMOL) Universit\u00e9 Constantine1 Constantine Algeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boumaraf","family":"Manel","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de recherche: Valorisation des Ressources Naturelles, Mol\u00e9cules Bioactives et Analyses Physico\u2010Chimiques et Biologiques (VARENBIOMOL) Universit\u00e9 Constantine1 Constantine Algeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harsa","family":"Bouchra","sequence":"additional","affiliation":[{"name":"Faculty of Science, Laboratory of Plant Biology and Environment (LBVE), Axis: Medicinal Plants and Natural Substances University of Badji Mokhtar Annaba Algeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Bouchaala","family":"Anter","sequence":"additional","affiliation":[{"name":"Laboratoire de Biotechnologie, Ecole Nationale Sup\u00e9rieure de Biotechnologie Ville Universitaire Ali Mendjeli Constantine Algeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bensouici","family":"Chawki","sequence":"additional","affiliation":[{"name":"Biotechnology Research Centre Constantine Algeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5283-3501","authenticated-orcid":false,"given":"Mekkiou","family":"Ratiba","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de recherche: Valorisation des Ressources Naturelles, Mol\u00e9cules Bioactives et Analyses Physico\u2010Chimiques et Biologiques (VARENBIOMOL) Universit\u00e9 Constantine1 Constantine Algeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,22]]},"reference":[{"issue":"6","key":"e_1_2_11_2_1","first-page":"143","article-title":"Benefits of essential oil","volume":"8","author":"Tanu B.","year":"2016","journal-title":"Journal of Chemical and Pharmaceutical Research"},{"volume-title":"Essential Oil Safety, A Guide For Health Care Professionals","year":"2014","author":"Tisserand R.","key":"e_1_2_11_3_1"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3923\/ijp.2024.403.425"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.15376\/biores.18.1.1554\u20101576"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13399\u2010023\u201005162\u20100"},{"volume-title":"Nouvelle Flore d'Alg\u00e9rie et des R\u00e9gions D\u00e9sertiques M\u00e9ridionales","year":"1963","author":"Qu\u00e8zel P.","key":"e_1_2_11_7_1"},{"key":"e_1_2_11_8_1","first-page":"23","article-title":"Pastoral Plants for Rehabilitation of Degraded Soil in Tunisia: The Case for Use of Calicotome villosa and Genista spachiana (Fabaceae)","volume":"63","author":"Mechergui K.","year":"2017","journal-title":"Biologija"},{"key":"e_1_2_11_9_1","first-page":"58","article-title":"In vitro Antioxidant Activity of Oudneya africana R. Br. Aerial Parts","volume":"4","author":"Nabti L. Z.","year":"2016","journal-title":"IBSPR 2016"},{"key":"e_1_2_11_10_1","unstructured":"M. D.Ouldel Hadj M.Hadj Mahammed H.Zabeirou andA.Chehma Importance des plantes spontan\u00e9es m\u00e9dicinales la pharmacologie traditionnelle la r\u00e9gion d'Ouargla (Sahara septentrional\u2014Est alg\u00e9rienne) D\u00e9partement de Biologie Facult\u00e9 des Sciences et Sciences de l'Ing\u00e9nieur Laboratoire de protection des \u00e9cosyst\u00e8mes en milieu aride et semi\u2010aride Universit\u00e9 de Ouargla BP 163 Ouargla 30000 Alg\u00e9rie.76p. 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