{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T07:59:18Z","timestamp":1780646358326,"version":"3.54.1"},"reference-count":47,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:00:00Z","timestamp":1740182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:00:00Z","timestamp":1740182400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","award":["RSPD2025R676"],"award-info":[{"award-number":["RSPD2025R676"]}],"id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Cymbopogon commutatus<\/jats:italic>\n                    has been used as an ingredient in the manufacturing of soap and mosquito repellent. Herein, the chemical profiling of the\n                    <jats:italic>C. commutatus<\/jats:italic>\n                    aerial parts essential oil (CCEO) was constructed on the basis of the multiplex of GC\u2013MS and nuclear magnetic resonance (NMR). Four nanoformulations\u2014EO nanoemulsions (CCEO@NE), chitosan\u2010coated (CSNPs@NE), silver nanoparticle\u2013loaded (AgNPs@NE), and iron oxide\u2013loaded (Fe\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>3<\/jats:sub>\n                    NPs@NE)\u2014were formulated. The larvicidal effects of CCEO, its major component, and its nanoformulations were evaluated on\n                    <jats:italic>Culex pipiens<\/jats:italic>\n                    . Twenty\u2010seven components (99.77%)\u2014including monoterpenes (78.36%) and sesquiterpenes (21.41%)\u2014were tentatively identified, including geraniol (67.49%) and geranyl acetate (3.52%) as predominant constituents. Geraniol was isolated and confirmed via NMR spectroscopic analysis. The nanoformulations exhibited diverse characteristics, with particle sizes spanning from 81.28\u00a0\u00b1\u00a06.17\u00a0nm (CCEO@NE) to 128.67\u00a0\u00b1\u00a06.96\u00a0nm (Fe\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>3<\/jats:sub>\n                    NPs@NE) and encapsulation efficiencies ranging from 72.57%\u00a0\u00b1\u00a04.05% (Fe\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>3<\/jats:sub>\n                    NPs@NE) to 83.73%\u00a0\u00b1\u00a06.69% (CCEO@NE). Zeta potentials ranged from \u221221.38\u00a0\u00b1\u00a05.18\u00a0mV (AgNPs@NE) to +14.39\u00a0\u00b1\u00a02.19\u00a0mV (CSNPs@NE), indicating variations in surface charge stability. CCEO and geraniol showed the highest larvicidal effects, recording LC\n                    <jats:sub>50<\/jats:sub>\n                    of 263.96 and 226.41\u00a0ppm, respectively, after 48\u00a0h of exposure. Nanoformulations showed latent effects and inhibitory activity in pupation and fly emergence. Consequently, CCEO and its nanoformulations may present good alternatives for controlling\n                    <jats:italic>C. pipiens<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202403276","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T04:48:39Z","timestamp":1739249319000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Larvicidal Effects of\n                    <i>Cymbopogon commutatus<\/i>\n                    Essential Oil and Its Based Nanoformulations on\n                    <i>Culex pipiens<\/i>\n                    : Chemical Profiling and Physicochemical Characterization"],"prefix":"10.1002","volume":"22","author":[{"given":"Mai M.","family":"Elghonemy","sequence":"first","affiliation":[{"name":"Department of Natural Compounds Chemistry National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fathalla","family":"Ayoob","sequence":"additional","affiliation":[{"name":"Chemistry of Tanning Materials and Leather Technology Department National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoda S. M.","family":"Abdel\u2010Ghany","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Animal Diseases National Research Centre  Giza Egypt"},{"name":"Ticks and Tick\u2010Born Diseases Research Unit, National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulsalam M.","family":"Kassem","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy (Boys) Al\u2010Azhar University, Nasr City  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abd El\u2010Nasser G.","family":"El\u2010Gendy","sequence":"additional","affiliation":[{"name":"Medicinal and Aromatic Plants Research Department National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sobhy","family":"Abdel\u2010Shafy","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Animal Diseases National Research Centre  Giza Egypt"},{"name":"Ticks and Tick\u2010Born Diseases Research Unit, National Research Centre  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed M.","family":"Abd\u2010ElGawad","sequence":"additional","affiliation":[{"name":"Plant Production Department College of Food &amp; Agriculture Sciences King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Imagawa","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences Tokushima Bunri University  Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3302-3623","authenticated-orcid":false,"given":"Abdelsamed I.","family":"Elshamy","sequence":"additional","affiliation":[{"name":"Department of Natural Compounds Chemistry National Research Centre  Giza Egypt"},{"name":"Faculty of Pharmaceutical Sciences Tokushima Bunri University  Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,22]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Olfactory Concepts Insect Control to Insectic","author":"Vega R\u00faa A.","year":"2019"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2020.112944"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2019.01.019"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2024.119060"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22020205"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.31661\/gmj.v8i0.1532"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2020.08.086"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27217298"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2024.141227"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/02652048.2017.1328464"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10311-020-01142-2"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.997918"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2024.118181"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2021.10.070"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28020543"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopen.2017.03.004"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.7763\/IJCEA.2014.V5.360"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/0972060X.2016.1231087"},{"key":"e_1_2_10_20_1","volume-title":"Identification of Essential Oil Components by Gas Chromatography\/Mass Spectrometry","author":"Adams R. 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