{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T06:16:24Z","timestamp":1782022584104,"version":"3.54.5"},"reference-count":113,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp; Biodiversity"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Pterocarpus soyauxii (P. soyauxii)<\/jats:italic> is a Fabaceae family traditionally used to treat menopausal disorders. This study aims to investigate the effect of <jats:italic>P. soyauxii<\/jats:italic> on menopause\u2010related non\u2010alcoholic fatty liver disease (NAFLD) and to determine its mechanisms of action and signaling pathways. The pharmacokinetic and dynamic properties and the toxicological profile of <jats:italic>P. soyauxii<\/jats:italic> compounds were assessed using the SwissADME and Protox III databases. A pharmacology network was constructed to identify active compound targets and corresponding genes. Compound target and protein\u2013protein interaction networks were created using Cytoscape software. Molecular docking studies were conducted to assess the binding affinity of <jats:italic>P. soyauxii<\/jats:italic> compounds with specific proteins. In vitro experiments evaluated the antioxidant properties of <jats:italic>P. soyauxii<\/jats:italic>. In vivo studies using ovariectomized (Ovx) rat models underlined pathways and effects of <jats:italic>P. soyauxii<\/jats:italic> on biochemical and histological features linked with NAFLD. Findings suggest that <jats:italic>P. soyauxii<\/jats:italic> compounds are readily absorbed through the intestine and exhibit a relatively low level of toxicity. Protein\u2013protein interaction, compound\u2010target networks, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed several pathways and target proteins of <jats:italic>P. soyauxii<\/jats:italic> compounds. Indeed, they target specific proteins such as estrogen receptor alpha\/beta ER\u03b1\/\u03b2, nicotinamide adenine dinucleotide phosphate oxidase (NADPH\u2010O), epidermal growth factor receptor (EGFR), MAPK1, peroxisome proliferator\u2010activated receptors alpha\/gamma (PPAR\u03b1\/G), and HMG\u2010CoA reductase. Molecular docking revealed that <jats:italic>P. soyauxii<\/jats:italic> compounds demonstrate high binding affinity to various proteins. In vitro, <jats:italic>P. soyauxii<\/jats:italic> inhibits the oxidative power of OH, H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>, and NO. In vivo<jats:italic>, P. soyauxii<\/jats:italic> significantly (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001, and <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01, respectively) reduces ALAT (25.14%), hepatic cholesterol (15.27%), and malondialdehyde (MDA) (26.78%) levels at 200\u00a0mg\/kg and prevents steatosis in the liver. These findings suggest that <jats:italic>P. soyauxii<\/jats:italic> may have a protective role against menopause\u2010related NAFLD.<\/jats:p>","DOI":"10.1002\/cbdv.202403384","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T12:33:59Z","timestamp":1739882039000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Exploring the Effects of <i>Pterocarpus Soyauxii<\/i> Against Menopause\u2010Related NAFLD Based on Network Pharmacology, Molecular Docking, and Experimental Validation"],"prefix":"10.1002","volume":"22","author":[{"given":"Owona Pascal","family":"Emmanuel","sequence":"first","affiliation":[{"name":"Department of Animal Biology and Physiology Laboratory of Animal Physiology, Faculty of Science University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1414-4174","authenticated-orcid":false,"given":"Mengue Ngadena Yolande","family":"Sandrine","sequence":"additional","affiliation":[{"name":"Department of Animal Biology and Physiology Laboratory of Animal Physiology, Faculty of Science University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"},{"name":"Neurosciences and Psychogerontology Axis, Laboratory of Development and Maldevelopment, Department of Psychology, Faculty of Arts, Letters, and Social Science University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilanda Danielle","family":"Claude","sequence":"additional","affiliation":[{"name":"Department of Animal Biology and Physiology Laboratory of Animal Physiology, Faculty of Science University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bidingha A. Goufani","family":"Ronald","sequence":"additional","affiliation":[{"name":"Department of Animal Biology and Physiology Laboratory of Animal Physiology, Faculty of Science University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ama Moor","family":"Vicky","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biomedical Sciences Clinical Biochemistry Laboratory University Hospital Centre Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dzeufiet Djomeni Paul","family":"D\u00e9sir\u00e9","sequence":"additional","affiliation":[{"name":"Department of Animal Biology and Physiology Laboratory of Animal Physiology, Faculty of Science University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamtchouing","family":"Pierre","sequence":"additional","affiliation":[{"name":"Department of Animal Biology and Physiology Laboratory of Animal Physiology, Faculty of Science University of Yaound\u00e9 1 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Aziz","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Health Food Hygiene and Quality University of Ioannina Arta Greece"},{"name":"Institute of Molecular Biology and Biotechnology The University of Lahore Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulhakeem S.","family":"Alamri","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sciences, The faculty of Applied Medical Sciences Taif University Taif Saudi\u00a0Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walaa F.","family":"Alsanie","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sciences, The faculty of Applied Medical Sciences Taif University Taif Saudi\u00a0Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid","family":"Alhomrani","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sciences, The faculty of Applied Medical Sciences Taif University Taif Saudi\u00a0Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/AITC202107200"},{"key":"e_1_2_12_3_1","article-title":"Endocrine Changes in Postmenopausal Women: A Comprehensive View","volume":"15","author":"Motlani V.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.5.591"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.21926\/obm.geriatr.2303248"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10051184"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2023.100835"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2014.00037"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11040689"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12227058"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12291-014-0446-0"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10060890"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11061131"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2008.06.016"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12091653"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.870239"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.3058"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6889533"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/livers2010003"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v7.i10.1325"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1237845"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13659-024-00445-z"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.3.927"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.984241"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare12111081"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.628690"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1389329"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.46.30131"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2009.10.014"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-41145-5"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-63657-8_7"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/757461"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-022-01640-y"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-023-01782-7"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1665-2681(19)31502-9"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0205034"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2018.12.014"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k4810"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.4103\/tcmj.tcmj_86_20"},{"key":"e_1_2_12_40_1","first-page":"61","article-title":"Obesity in Menopause\u2014Our Negligence or an Unfortunate Inevitability?","volume":"16","author":"Kozakowski J.","year":"2017","journal-title":"Menopause Review\/Przegl\u0105d Menopauzalny"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1080\/09513590.2024.2312885"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0238868"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharma3020013"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/617459"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2018-000895"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2017.11.002"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15020317"},{"key":"e_1_2_12_48_1","article-title":"Estrogenic and Antioxidant Activities of Pterocarpus soyauxii (Fabaceae) Heartwood Aqueous Extract in Bilateral Oophorectomized Wistar Rat","volume":"2021","author":"Mengue N. Y. S.","year":"2021","journal-title":"Evidence\u2010Based Complementary and Alternative Medicine"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.9734\/jocamr\/2023\/v21i1425"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e33843"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-3380-7_1"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/10.6.1003"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2003.09.005"},{"key":"e_1_2_12_54_1","first-page":"305","article-title":"The Thiobarbituric Acid Reagent as a Test for the Oxidation of Unsaturated Fatty Acids by Various Agents","volume":"24","author":"Wilbur K. M.","year":"1949","journal-title":"Archives of Biochemistry and Biophysics"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(59)90090-6"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(82)90118-X"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2009.197"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1210\/endocr\/bqaa134"},{"key":"e_1_2_12_59_1","first-page":"1","article-title":"Triglyceride Metabolism in the Liver","volume":"12","author":"Alves\u2010Bezerra M.","year":"2017","journal-title":"Comprehensive Physiology"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-05766-y"},{"issue":"208","key":"e_1_2_12_61_1","first-page":"46","article-title":"Some Aspects of Pathogenesis of Nonalcoholic Fatty Liver Disease in Postmenopausal Women","author":"Parkosadze G.","year":"2012","journal-title":"Georgian Medical News"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i3.237"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1202348"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.3109\/13697130903009203"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-63579-3"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2010.198"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2011-12-8-r75"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.111.240754"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201400314"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)40436-4"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0215593"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-4108"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-013-0758-5"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0210828"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2021.1961072"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1124003"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2017.1291340"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-020-02962-z"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10020174"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/livers2040023"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/biof.5520170128"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/792639"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2006.05.010"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.210237"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M105945200"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90269-0"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrrev.2011.12.005"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2012.06.053"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12082456"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1078\/0944-7113-00331"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.33.1.177"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.24.351"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfh147"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40203-015-0008-z"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9547613"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu7105434"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5577498"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2016.2674"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.3164\/jcbn.2008047"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2005.08.007"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0161430"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13098-022-00814-z"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13060627"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.07.024"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.07.1148"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2022.04.014"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40200-020-00491-7"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.14256"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2009.12.005"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-511X-10-49"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.4093\/dmj.2013.37.4.278"},{"key":"e_1_2_12_112_1","first-page":"1291","article-title":"NAFLD as a Sexual Dimorphic Disease: Role of Gender and Reproductive Status in the Development and Progression of Nonalcoholic Fatty Liver Disease and Inherent Cardiovascular Risk","volume":"34","author":"Ballestri S.","year":"2017","journal-title":"Advances in Aerapy"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2021.1901739"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.11648\/j.jdmp.20220801.11"}],"container-title":["Chemistry &amp; Biodiversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbdv.202403384","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T18:21:00Z","timestamp":1753294860000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cbdv.202403384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,14]]},"references-count":113,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/cbdv.202403384"],"URL":"https:\/\/doi.org\/10.1002\/cbdv.202403384","archive":["Portico"],"relation":{},"ISSN":["1612-1872","1612-1880"],"issn-type":[{"value":"1612-1872","type":"print"},{"value":"1612-1880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,14]]},"assertion":[{"value":"2024-12-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202403384"}}