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The extracts were prepared by maceration using hexane (EBH), dichloromethane (EBD), and ethyl acetate (EBAE), and they were evaluated for their antiproliferative potential through a 3\u20104,5\u2010dimethyl\u2010thiazol\u20102\u2010yl\u20102,5\u2010diphenyltetrazoliumbromide (MTT) assay in the cervical cancer cell culture (HeLa cell line) and a non\u2010cancer cell line (NIH\u20103T3). EBH, EBD, and EBAE were cytotoxic in HeLa cells, with 50% inhibition concentration (IC\n                    <jats:sub>50<\/jats:sub>\n                    ) = 97.59, 31.03, and 57.67 \u00b5g\/mL, respectively. EBD inhibited migration and altered the cell cycle. Eight compounds were tentatively assigned to\n                    <jats:italic>E. brasiliensis<\/jats:italic>\n                    leaf extracts by interpreting their fragmentation patterns and molecular formulae obtained from mass spectra. The dichloromethane extract of the leaves of\n                    <jats:italic>E. brasiliensis<\/jats:italic>\n                    against the cells of cervical cancer showed potential cytotoxicity activity.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.202500429","type":"journal-article","created":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T17:15:11Z","timestamp":1744478111000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["<i>Eugenia brasiliensis<\/i>\n                    : Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential"],"prefix":"10.1002","volume":"22","author":[{"given":"Giovana G. F. 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